159499-99-7Relevant academic research and scientific papers
Synthesis and biological evaluation of certain alkenyldiarylmethanes as anti-HIV-1 agents which act as non-nucleoside reverse transcriptase inhibitors
Cushman, Mark,Golebiewski, W. Marek,Graham, Lisa,Turpin, Jim A.,Rice, William G.,Fliakas-Boltz, Valerie,Buckheit Jr., Robert W.
, p. 3217 - 3227 (2007/10/03)
Several novel alkenyldiarylmethane (ADAM) non-nucleoside HIV-1 reverse transcriptase inhibitors were synthesized. The most potent of these proved to be 3',3'-dibromo-4',4'-dimethoxy-5',5'-bis(methoxycarbonyl)-1,1-diphenyl-1- heptene (8). ADAM 8 inhibited
