130883-74-8

Basic information

• Product Name: 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane
• Synonyms: 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane
• CAS NO: 130883-74-8
• Molecular Weight: 446.049
• Mol File: 130883-74-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane(130883-74-8)
• EPA Substance Registry System: 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane(130883-74-8)

Safety Data

• Hazardous Substances Data: 130883-74-8(Hazardous Substances Data)

Upstream product

• 28165-45-9 methyl 3-bromo-2-hydroxybenzoate 
• 50-00-0 formaldehyd 
• 3883-95-2 3-bromosalicylic acid 
• 942296-83-5 C₁₇H₁₄O₆Br₂ 

Downstream Products

• 159499-99-7 methyl-3-bromo-5-(1-(5-bromo-4-methoxy-3-(methoxycarbonyl)phenyl)hept-1-enyl)-2-methoxybenzoate 
• 159499-98-6 [3',3''-dibromo-4',4''-dimethoxy-5',5''-di(methoxycarbonyl)diphenyl]methanone 
• 159499-97-5 3,3'-dibromo-4,4'-dimethoxy-5,5'-bis(methoxycarbonyl)diphenylmethane 

Relevant articles and documents

Methylenedisalicylic acid derivatives: New PTP1B inhibitors that confer resistance to diet-induced obesity

Methylenedisalicylic acid derivatives were synthesized and their inhibitory activities against protein tyrosine phosphatases (PTPases) examined. Two of the compounds, 8 and 9, showed Ki values of 9.4 and 6.3 μM against PTP1B, 4- and 7-fold lower values compared to those against TC-PTP. They were reversible and slow-binding inhibitors against PTP1B. When compound 8 was fed to a mouse model, the weight gain and adipocyte fat storage induced by a high-fat-diet were significantly suppressed.