130883-74-8

Upstream product

• 50-00-0 formaldehyd 
• 3883-95-2 3-bromosalicylic acid 
• 942296-83-5 C₁₇H₁₄O₆Br₂ 
• 28165-45-9 methyl 3-bromo-2-hydroxybenzoate 

Downstream Products

• 159499-99-7 methyl-3-bromo-5-(1-(5-bromo-4-methoxy-3-(methoxycarbonyl)phenyl)hept-1-enyl)-2-methoxybenzoate 
• 159499-98-6 [3',3''-dibromo-4',4''-dimethoxy-5',5''-di(methoxycarbonyl)diphenyl]methanone 
• 159499-97-5 3,3'-dibromo-4,4'-dimethoxy-5,5'-bis(methoxycarbonyl)diphenylmethane 

Relevant academic research and scientific papers

Methylenedisalicylic acid derivatives: New PTP1B inhibitors that confer resistance to diet-induced obesity

Methylenedisalicylic acid derivatives were synthesized and their inhibitory activities against protein tyrosine phosphatases (PTPases) examined. Two of the compounds, 8 and 9, showed Ki values of 9.4 and 6.3 μM against PTP1B, 4- and 7-fold lower values compared to those against TC-PTP. They were reversible and slow-binding inhibitors against PTP1B. When compound 8 was fed to a mouse model, the weight gain and adipocyte fat storage induced by a high-fat-diet were significantly suppressed.

Synthesis and Anti-HIV Activities of Low Molecular Weight Aurintricarboxylic Acid Fragments and Related Compounds

Several compounds corresponding to fragments of the schematic representation of the polymeric structure of aurintricarboxylic acid (ATA) have been prepared and tested for prevention of the cytopathic effect of HIV-1 and HIV-2 in MT-4 cell culture and HIV-