159500-11-5

Basic information

• Product Name: 3',3''-dichloro-4-hydroxy-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene
• Synonyms: 3',3''-dichloro-4-hydroxy-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene
• CAS NO: 159500-11-5
• Molecular Weight: 469.318
• Mol File: 159500-11-5.mol

Chemical Properties

• CAS DataBase Reference: 3',3''-dichloro-4-hydroxy-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene(CAS DataBase Reference)
• NIST Chemistry Reference: 3',3''-dichloro-4-hydroxy-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene(159500-11-5)
• EPA Substance Registry System: 3',3''-dichloro-4-hydroxy-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene(159500-11-5)

Safety Data

• Hazardous Substances Data: 159500-11-5(Hazardous Substances Data)

Upstream product

• 154023-65-1 3,3'-dichloro-4,4'-dimethoxy-5,5'-bis(methoxycarbonyl)benzophenone 
• 207743-09-7 3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-4-[(tert-butyldiphenylsilyl)oxy]-1-butene 
• 159500-10-4 4-[(tert-butyldimethylsilyl)oxy]-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene 

Downstream Products

• 207743-11-1 4-azido-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene 
• 261786-54-3 N-(5α-cholestan-3β-yl)-4,4-bis(3-chloro-4-methoxy-5-methoxycarbonylphenyl)-3-butenamide 
• 261786-55-4 N-(5α-cholestan-3α-yl)-4,4-bis(3-chloro-4-methoxy-5-methoxycarbonylphenyl)-3-butenamide 
• 230646-84-1 4,4-bis(3-chloro-4-methoxy-5-methoxycarbonylphenyl)-3-butenoic acid 
• 207743-10-0 3',3''-dichloro-4-methanesulfonyloxy-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene 

Relevant articles and documents

New alkenyldiarylmethanes with enhanced potencies as anti-HIV agents which act as non-nucleoside reverse transcriptase inhibitors

Twenty-two new alkenyldiarylmethanes (ADAMs) were synthesized and evaluated for inhibition of HIV-1 replication. The most potent compound proved to be methyl 3',3'-dichloro-4',4'dimethoxy-5',5'-bis(methoxycarbonyl)- 6,6-diphenyl-5-hexenoate (ADAM II), whi

Synthesis and biological evaluation of certain alkenyldiarylmethanes as anti-HIV-1 agents which act as non-nucleoside reverse transcriptase inhibitors

Several novel alkenyldiarylmethane (ADAM) non-nucleoside HIV-1 reverse transcriptase inhibitors were synthesized. The most potent of these proved to be 3',3'-dibromo-4',4'-dimethoxy-5',5'-bis(methoxycarbonyl)-1,1-diphenyl-1- heptene (8). ADAM 8 inhibited