1595276-12-2Relevant academic research and scientific papers
Stereocontrolled syntheses of tetralone- and naphthyl-type lignans by a one-pot oxidative [3,3] rearrangement/friedel-crafts arylation
Reddel, Jordan C. T.,Lutz, Kelly E.,Diagne, Abdallah B.,Thomson, Regan J.
, p. 1395 - 1398 (2014/03/21)
The development of a stereoselective one-pot oxidative [3,3] sigmatropic rearrangement/Friedel-Crafts arylation that provides enantioenriched benzhydryl compounds is reported. The utility of this new transformation is demonstrated by the concise synthesis of several tetralone- and naphthyl-type lignan natural products, many of which display anti-malarial activity.
