159547-26-9Relevant articles and documents
Potent and orally active angiotensin II receptor antagonists with equal affinity for human AT1 and AT2 subtypes
Chang,Ashton,Flanagan,Chen,O'Malley,Zingaro,Kivlighn,Siegl,Lotti,Chang,Greenlee
, p. 3741 - 3758 (2007/10/03)
In order to block the effects induced by the interactions between angiotensin II (AII) and both AT1 and AT2 receptors, we have pursued the discovery of orally active non-peptide AII antagonists that exhibit potent and equal affinity
SUBSTITUTED 1,2,4-TRIAZOLES BEARING ACIDIC FUNCTIONAL GROUPS AS ANGIOTENSIN II ANTAGONISTS
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, (2008/06/13)
Novel substituted triazolinone, triazolinethione, and triazolinimine compounds of the formula I are useful as angiotensin II antagonists. STR1