159553-95-4Relevant academic research and scientific papers
Facile synthesis of N-substituted isothiazol-3(2H)-ones using a hypervalent iodine(III) reagent
Kang, Iou-Jiun,Wang, Huey-Min,Huang, Hsin-Yu,Chen, Ling-Ching
, p. 1185 - 1188 (2007/10/03)
Treatment of N-substituted (Z)-3-(benzylsulfanyl)propenamides (4) with phenyliodine(III) bis(trifluoroacetate) containing trifluoroacetic acid resulted in an interrupted Pummerer-type reaction to give N-substituted isothiazol-3(2H)-ones (5) rather than th
A General Synthesis of N-Substituted Isothiazol-3(2H)-ones
Beeley, Nigel R. A.,Harwood, Laurence M.,Hedger, Paul C.
, p. 2245 - 2252 (2007/10/02)
A general route to the synthesis of N-substituted isothiazol-3(2H)-ones (4a-i) is described which proceeds via trichloroacetic acid-mediated ring closure of N-substituted (Z)-3-(benzylsulfinyl)propenamides (15a-i).
