159573-36-1

Basic information

• Product Name: S-ethyl (2R,3S)-2-(tert-butyldimethylsiloxy)-3-hydroxy-3-phenylpropanethioate
• Synonyms: S-ethyl (2R,3S)-2-(tert-butyldimethylsiloxy)-3-hydroxy-3-phenylpropanethioate
• CAS NO: 159573-36-1
• Molecular Weight: 340.559
• Mol File: 159573-36-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: S-ethyl (2R,3S)-2-(tert-butyldimethylsiloxy)-3-hydroxy-3-phenylpropanethioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-ethyl (2R,3S)-2-(tert-butyldimethylsiloxy)-3-hydroxy-3-phenylpropanethioate(159573-36-1)
• EPA Substance Registry System: S-ethyl (2R,3S)-2-(tert-butyldimethylsiloxy)-3-hydroxy-3-phenylpropanethioate(159573-36-1)

Safety Data

• Hazardous Substances Data: 159573-36-1(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 138509-94-1 (Z)-1-(ethylthio)-1-(trimethylsiloxy)-2-(tert-butyldimethylsiloxy)ethene 
• 160114-64-7 S-ethyl 2-(t-butyldimethylsiloxy)ethanethioate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 67226-76-0 (tert-butyldimethylsiloxy) acetic acid tert-butyldimethylsilyl ester 
• 67226-78-2 ethyl 2-(tert-butyldimethylsilyloxy)acetate 
• 78826-45-6 2-((tert-butyldimethylsilyl)oxy)acetyl chloride 
• 105459-05-0 {[tert-butyl(dimethyl)silyl]oxy}acetic acid 

Relevant articles and documents

Preparation of both enantiomers of 2-methyl-3-hydroxythioesters based on chiral Lewis acid-controlled synthesis

Both enantiomers of 2-methyl-3-hydroxythioesters have been synthesized by using chiral tin(II) Lewis acid-mediated aldol reactions of (Z)-1-ethylthio-1-trimethylsiloxypropene (4) with aldehydes, based on chiral Lewis acid-controlled synthesis. The key to

Molecular recognition by artificial chiral catalysts utilizing a metal chelate. A remarkable difference in reactivity between geometrical isomers of silyl enolates in asymmetric aldol reactions using chiral Tin(II) catalysts

A remarkable difference in reactivity between (E)- and (Z)-enolates in the asymmetric aldol reactions of silyl enolates with adehydes using chiral tin(II) Lewis acids was found. This difference can be interpreted to mean that the chiral catalyst coordinat

Diastereo- and Enantioselective Synthesis of syn- and anti-1,2-Diol Units by Asymmetric Aldol Reactions

syn- and anti-1,2-Diol units were prepared by using asymmetric aldol reactions of the silyl enol ethers derived from α-alkoxythioacetic S-esters with aldehydes.In the presence of tin(II) triflate, a chiral diamine, and dibutyltin diacetate, (Z)-2-benzyloxy-1-ethylthino-1-(trimethylsiloxy)ethene reacted with aldehydes to afford the corresponding anti-aldol adducts in high yields with excellent diastereo- and enantioselectivities, while syn-adducts were obtained from (Z)-2-(t-butyldimethylsiloxy)-1-ethylthio-1-(trimethylsiloxy)ethene and aldehydes under the same reaction conditions.Thus, both diastereomers can be synthesized in excellent enantiomeric excesses by simply choosing the protective groups of the alkoxyl parts of the silyl enol ethers.