159591-45-4Relevant academic research and scientific papers
DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES
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, (2021/06/22)
The present invention is concerned with deuterium-enriched substituted phenoxy-(3, 4-methylenedioxy)phenylacetic acid and acylsulfonamide derivatives of general structural formula I, their optically active or pure enantiomers and diastereomers, and pharmaceutical salts thereof, Formula (I) These compounds have selective antagonist activity for endothelin receptors or both endothelin and angiotensin II receptors, and are useful in the treatment of diseases mediated by endothelin and angiotensin-II and their receptors.
ENDOTHELIN ANTAGONISTS BEARING PYRIDYL AMIDES
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, (2008/06/13)
Phenoxyphenylacetic acids and derivatives of the general structural formula I STR1 have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac i
Endothelin antagonists bearing 5-membered heterocyclic amides
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, (2008/06/13)
Phenoxyphenylacetic acids and derivatives of the general structural formula I STR1 have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac i
Phenoxyphenylacetic acids and derivatives useful as endothelin antagonists.
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, (2008/06/13)
Phenoxyphenylacetic acids and derivatives of the general structural formula I STR1 have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac i
