159591-67-0

Upstream product

• 865139-45-3 methyl 3-bromo-4-((2-methylallyl)oxy)benzoate 
• 865138-24-5 methyl 3-bromo-4-hydroxy-5-(2-methylallyl)benzoate 
• 29415-97-2 methyl 3-bromo-4-hydroxybenzoate 
• 14348-41-5 3-bromo-4-hydroxy-benzoic acid 
• 1142225-87-3 methyl 3-(2-methyl-1-propenyl)-4-(tetrahydro-2H-pyran-2-yloxy)benzoate 
• 1142224-41-6 methyl 3-bromo-4-(tetrahydro-2H-pyran-2-yloxy)benzoate 
• 565450-40-0 methyl 4-hydroxy-3-(2-methyl-1-propenyl)benzoate 

Downstream Products

• 1142225-89-5 methyl 3-(2-methylpropyl)-4-(((trifluoromethyl)sulfonyl)oxy)benzoate 
• 865138-99-4 [4-(diphenylmethoxy)-3-isobutylphenyl]methanol 
• 159591-46-5 ethyl α-(2-iso-butyl-4-carbomethoxy-phenoxy)-3,4-methylenedioxyphenylacetate 
• 865138-98-3 methyl 4-(diphenylmethoxy)-3-isobutylbenzoate 

Relevant academic research and scientific papers

SPIROCYCLIC GPR40 MODULATORS

The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula IA, IB, I'A or I'B, where the definitions of the variables are provided herein. The present invention also

CONFORMATIONALLY CONSTRAINED CARBOXYLIC ACID DERIVATIVES USEFUL FOR TREATING METABOLIC DISORDERS

The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I or the general formula III: where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.

AMINOPHENYLPROPANOIC ACID DERIVATIVE

A compound represented by the formula (1): wherein each symbol is as defined in the specification, and a salt thereof and a prodrug thereof unexpectedly have superior GPR40 receptor agonist activity, superior in the properties as a pharmaceutical product such as stability and the like, and can be a safe and useful pharmaceutical agent as a drug for the prophylaxis or treatment of GPR40 receptor related pathology or diseases such as diabetes and the like.