159610-82-9

Basic information

• Product Name: FMOC-L-STYRYLALANINE
• Synonyms: (S)-N-FMOC-STYRYLALANINE;(S)-N-(9-FLUORENYLMETHOXYCARBONYL)-2-AMINO-5-PHENYL-4-PENTENOIC ACID;(S)-2-(FMOC-AMINO)-5-PHENYL-4-PENTENOIC ACID;RARECHEM BK PT 0179;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-2-STYRYL-L-ALANINE;FMOC-3-STYRYL-L-ALANINE;FMOC-L-STYRYLALANINE;FMOC-ALA(STYR)-OH
• CAS NO: 159610-82-9
• Molecular Formula: C₂₆H₂₃NO₄
• Molecular Weight: 413.47
• Mol File: 159610-82-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 141.7 °C
• Boiling Point: 532.63°C (rough estimate)
• Flash Point: 367 °C
• Appearance: /
• Density: 1.2217 (rough estimate)
• Vapor Pressure: 1.31E-19mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• Storage Temp.: 2-8°C
• PKA: 3.77±0.10(Predicted)
• CAS DataBase Reference: FMOC-L-STYRYLALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-L-STYRYLALANINE(159610-82-9)
• EPA Substance Registry System: FMOC-L-STYRYLALANINE(159610-82-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 159610-82-9(Hazardous Substances Data)

Usage

Description

FMOC-L-STYRYLALANINE, also known as N-(9-fluorenylmethoxycarbonyl)-L-styrylalanine, is a synthetic amino acid derivative that plays a crucial role in the field of peptide chemistry. It is characterized by its white to light grey powder form and is widely utilized in the synthesis of various peptides with diverse applications.

Uses

Used in Pharmaceutical Industry:
FMOC-L-STYRYLALANINE is used as a reactant for the preparation of peptides with antiangiogenic activity. These peptides have the potential to inhibit the formation of new blood vessels, which is a critical process in the growth and metastasis of cancerous tumors. By disrupting angiogenesis, these peptides can help in the development of novel therapeutic strategies against various types of cancer.
Additionally, FMOC-L-STYRYLALANINE can be employed in the synthesis of other bioactive peptides with potential applications in various therapeutic areas, such as inflammation, pain management, and central nervous system disorders. Its unique chemical properties make it a valuable building block for the development of innovative peptide-based drugs.

InChI:InChI=1/C26H23NO4/c28-25(29)24(16-8-11-18-9-2-1-3-10-18)27-26(30)31-17-23-21-14-6-4-12-19(21)20-13-5-7-15-22(20)23/h1-15,23-24H,16-17H2,(H,27,30)(H,28,29)/p-1/b11-8+/t24-/m0/s1

Upstream product

• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 

Downstream Products

• 909778-26-3 [(S)-1-((E)-(S)-1-Carbamoyl-4-phenyl-but-3-enylcarbamoyl)-propyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Single chain peptide compounds having hemoregulatory activity

There is disclosed single chain peptide compounds, substituted at a Cα-atom of a non-terminal amino acid by a group--A which is defined in claim 1. The native α-side chain of the Cα atom bonded group to group --A absent. The peptide derivatives according