1596243-42-3

Basic information

• Product Name: 2-(4-chlorophenyl)-7-fluoroquinazoline
• Synonyms: 2-(4-chlorophenyl)-7-fluoroquinazoline
• CAS NO: 1596243-42-3
• Molecular Weight: 258.682
• Mol File: 1596243-42-3.mol

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenyl)-7-fluoroquinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-7-fluoroquinazoline(1596243-42-3)
• EPA Substance Registry System: 2-(4-chlorophenyl)-7-fluoroquinazoline(1596243-42-3)

Safety Data

• Hazardous Substances Data: 1596243-42-3(Hazardous Substances Data)

Upstream product

• 61150-57-0 2-bromo-4-fluorobenzyl bromide 
• 104-88-1 4-chlorobenzaldehyde 

Relevant articles and documents

Synthesis of quinazolines and tetrahydroquinazolines: Copper-catalyzed tandem reactions of 2-bromobenzyl bromides with aldehydes and aqueous ammonia or amines

An efficient synthesis of diversely substituted quinazolines and 1,2,3,4-tetrahydroquinazolines through copper-catalyzed tandem reactions of the readily available 2-bromobenzyl bromides, aldehydes, and aqueous ammonia or amines has been developed. By using ammonia and simple aliphatic amines as the nitrogen source, the present method provides a versatile and practical protocol for the synthesis of quinazolines and 1,2,3,4-tetrahydroquinazolines. Copper on the beat: An efficient, simple and economical synthesis of diversely substituted quinazolines and 1,2,3,4-tetrahydroquinazolines has been developed through copper-catalyzed tandem reactions of the readily available 2-bromobenzyl bromides, aldehydes, and aqueous ammonia or simple aliphatic amines. Copyright