61150-57-0

Basic information

• Product Name: 2-Bromo-1-(bromomethyl)-4-fluorobenzene
• Synonyms: 2-BROMO-4-FLUOROBENZYL BROMIDE;2-BROMO-1-(BROMOMETHYL)-4-FLUOROBENZENE;2-Bromo-4-Fluorobenzyl;2-BroMo-1-(broMoMeth;2-Bromo-1-(bromomethyl)-4-fluorobenzene, alpha,2-Dibromo-4-fluorotoluene;Benzene, 2-bromo-1-(bromomethyl)-4-fluoro-
• CAS NO: 61150-57-0
• Molecular Formula: C₇H₅Br₂F
• Molecular Weight: 267.92
• Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Fluorine series;alkyl bromide| alkyl Fluorine
• Mol File: 61150-57-0.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 253.975 °C at 760 mmHg
• Flash Point: 107.4 °C
• Appearance: /Solid
• Density: 1.923 g/cm³
• Vapor Pressure: 0.028mmHg at 25°C
• Refractive Index: 1.583
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-Bromo-1-(bromomethyl)-4-fluorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-1-(bromomethyl)-4-fluorobenzene(61150-57-0)
• EPA Substance Registry System: 2-Bromo-1-(bromomethyl)-4-fluorobenzene(61150-57-0)

Safety Data

• RIDADR: 3261
• HazardClass: 8
• PackingGroup: Ⅲ
• Hazardous Substances Data: 61150-57-0(Hazardous Substances Data)

Usage

Chemical Properties

white crystal powde

InChI:InChI=1/C7H5Br2F/c8-4-5-1-2-6(10)3-7(5)9/h1-3H,4H2

Upstream product

• 229027-89-8 (2-bromo-4-fluorophenyl)methanol 
• 1006-41-3 2-bromo-4-fluorobenzoic acid 
• 1422-53-3 2-bromo-4-fluorotoluene 

Downstream Products

• 530141-41-4 2-[(2-bromo-4-fluorophenyl)methyl]-1H-isoindole-1,3(2H)-dione 
• 223787-51-7 2-[2-(2-bromo-4-fluoro-phenyl)-ethyl]-phenylamine 
• 223787-56-2 N-{2-[2-(2-bromo-4-fluoro-phenyl)-ethyl]-phenyl}-formamide 
• 223787-43-7 (2-bromo-4-fluoro-benzyl)-phosphonic acid diethyl ester 

Relevant articles and documents

Aromatic amine derivative organic electroluminescent material and device thereof

The invention discloses an aromatic amine derivative organic electroluminescent material and a device thereof. The compound is a pyrene compound substituted with an aromatic amine, wherein the compound has a substituted or unsubstituted (hetero) aryl group and a pyrene compound substituted or unsubstituted aromatic amine structure of a (hetero) aryl group, which may be used as a light emitting material in an organic electroluminescent device. These novel compounds can provide better device performance, such as higher external quantum efficiency and narrower half-peak widths, and the like.

SPIROCYCLIC TETRAHYDROQUINAZOLINES

Provided are compounds represented by Formula I, wherein R3, A, A1, A2, A3, E, E1, E2, L, Q, Z, and (aa) are as defined in the specification, and the pharmaceutically acceptable salts and solvates thereof. Compounds of Formula (I) are KRAS inhibitors and are thus useful to treat cancer and other diseases.

Cross-coupling strategy for the synthesis of diazocines

Ethylene bridged azobenzenes are novel, promising molecular switches that are thermodynamically more stable in the (Z) than in the (E) configuration, contrary to the linear azobenzene. However, their previous synthetic routes were often not general, and yields were poorly reproducible, and sometimes very low. Here we present a new synthetic strategy that is both versatile and reliable. Starting from widely available 2-bromobenzyl bromides, the designated molecules can be obtained in three simple steps.