159640-83-2Relevant academic research and scientific papers
Nonpeptide glycoprotein IIb/IIIa inhibitors: Substituted quinazolinediones and quinazolinones as potent fibrinogen receptor antagonists
Liverton, Nigel J.,Armstrong, Donna J.,Claremon, David A.,Remy, David C.,Baldwin, John J.,Lynch, Robert J.,Zhang, Guixiang,Gould, Robert J.
, p. 483 - 486 (2007/10/03)
The synthesis and biological activity of a series of 3,6-substituted quinazolinediones and quinazolinones are described. The potent activity of these compounds as platelet aggregation inhibitors demonstrates the utility of these structures as central templates for nonpeptide RGD mimics.
