1597-36-0Relevant academic research and scientific papers
Process for 4,6-di-substituted 2-aminopyrimidines
-
, (2008/06/13)
New compounds useful as intermediates for biologically-active compounds have the formula I STR1 wherein Y is a group having the formula --CH2 X in which X is F, Cl, or Br, or Y is a group having the formula STR2 in which R2 is F, Cl or Br and R3 is H, F, Cl, Br or a group having the formula --CR4 R5 R6, in which R4, R5 and R6, independently, are F, Cl or Br; A is H, OH, SH, F, Cl, Br or a group --OR7 or --SR7 in which R7 is C1 -C4 straight- or branched chain alkyl, C2-4 straight- or branched chain alkyl substituted with 1 to 3 F, Cl or Br atoms, or A is a group --NR8 R9 in which R8 and R9, independently, are H, C1 -C4 straight- or branched chain alkyl or C3 -C4 alkenyl, or R8 and R9 together may form a C3 -C7 polymethylene chain, which is optionally interrupted by an oxygen atom; as well as salts of compounds of formula I with acids; provided that: when Y is CH2 F, then A is as hereinbefore defined other than OH, Cl or OCH3.
