159720-34-0

Upstream product

• 1002-18-2 3-(2-chlorocarbonyl-ethyldisulfanyl)-propionyl chloride 
• 2627-86-3 (S)-1-phenyl-ethylamine 

Downstream Products

• 159720-27-1 2-(S)-α-methyl benzyl-4-bromo-1,2-isothiazoline-3-one 
• 125458-23-3 2-((S)-1-Phenyl-ethyl)-isothiazol-3-one 
• 172656-76-7 2-(S)-α-methylbenzyl-4-bromo-1,2-isothiazoline-3-one-1-(S)-oxide 
• 159720-29-3 2-(S)-α-methyl benzyl-4-(1-ethoxyvinyl)-1,2-isothiazoline-3-one 

Relevant academic research and scientific papers

Facile palladium catalysed functionalisation of 1,2-isothiazoline-3-ones and the highly diastereoselective Diels-Alder reactions of 4-vinyl-1,2- isothiazoline-3-one-1-oxides

A rapid and convenient palladium catalysed method for the regioselective synthesis of a range of usefully functionalised, homochiral 4-substituted 1,2-isothiazoline-3-ones is reported. The totally diastereoselective Diels- Alder reactivity of semi-cyclic sulfoxide containing dienes, 4-vinyl-1,2- isothiazoline-3-one-1-oxides is discussed.