159727-25-0

Upstream product

• 672-30-0 (3-bromophenyl)pentafluoro-λ⁶-sulfane 
• 1165952-92-0 cyclohexa-1,4-diene 
• 89415-83-8 4,5-dichlorocyclohexene 
• 2557-81-5 pentafluorosulfanylbenzene 
• 654671-65-5 2,4,5-trichloropentafluorosulfanylcyclohexane 
• 2613-27-6 1-nitro-4-(pentafluorosulfanyl)benzene 
• 2993-24-0 4-(pentafluorosulfanyl)aniline 

Downstream Products

• 852333-48-3 2-methyl-4-(pentafluorosulfanyl)benzenamine 
• 1402070-57-8 2-bromo-1-iodo-4-(pentafluorosulfanyl)benzene 
• 1402070-58-9 1,1'-disulfanediylbis[2-bromo-4-(pentafluorosulfanyl)benzene] 
• 1402070-59-0 S-[2-bromo-4-(pentafluorosulfanyl)phenyl] benzenesulfonothioate 
• 1402070-60-3 [2-bromo-4-(pentafluorosulfanyl)phenylsulfanylethynyl]trimethylsilane 
• 1101866-14-1 2-allyl-4-(pentafluorosulfanyl)aniline 

Relevant academic research and scientific papers

Synthesis and properties of pentafluorosulfanyl group (Sf5)-containing meta-diamide insecticides

Herein, we describe novel pentafluorosulfanyl (SF5) group-containing meta-diamide insecticides. For the facile preparation of the SF5-based compounds 4a–d, practical synthetic methods were applied. Among newly synthesized compounds, 3-benzamido-N-(2,6-dimethyl-4-(pentafluoro-λ6-sulfanyl)phenyl)-2-fluorobenzamide 4d showed (i) a high insecticidal activity, (ii) an excellent selectivity to insects, and (iii) good levels of water solubility and log P values. In this study, we demonstrated that the pentafluorosulfanyl moiety could serve as an attractive functionality for the discovery of a new scope of crop-protecting agents.

2,4-DIAMINOPYRIMIDINE DERIVATIVES AS HISTAMINE H4 MODULATORS

The present invention relates to 2,4-diaminopyrimidines and pharmaceutically acceptable salts thereof, purification methods for the same, pharmaceutical compositions containing them, methods of obtaining and using them for the treatment of disease states,

BICYCLIC HETEROARYL DERIVATIVES AND PREPARATION AND USES THEREOF

Compounds of Formula (A), where the definition of the variables are as described in the description, as well as their preparation and uses, and pharmaceutical compositions comprising these compounds and their uses as modulators of dysfunctional glutamate

NOVEL BICYCLIC PYRIDINONES AS GAMMA-SECRETASE MODULATORS

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I I as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis,

Preparations and reactions of SF5-substituted aryl and heteroaryl derivatives via Mg and Zn organometallics

Polyfunctional SF5-substituted cycles: Several organometallic sequences using zinc, copper, and magnesium intermediates were developed to prepare a broad range of SF5-substituted aromatic and heterocyclic compounds of potential interest for pharmaceutical applications. Copyright

PENTAFLUOROSULFANYL-SUBSTITUTED PIPERAZINYLPIPERIDINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS

The present invention relates to pentaf luorosulfanyl substituted compounds that modulate the activity of or bind to chemokine receptors such as CCR5, rendering the compounds useful in the treatment of inflammatory diseases, immune diseases and viral infe

METHOD FOR PRODUCING 4-PENTAFLUORIDE-SULFANYL-BENZOYLGUANIDINES

The invention relates to a method for producing 4-pentafluoride-sulfanyl-benzoylguanidines of formula (I) wherein groups from R1 to R4 correspond to meanings given in claims. The compounds of the formula (I) constitute NHE1 inhibitors and can be used for

PENTAFLUOROSULFANYL BENZOYLGUANIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE AS MEDICAMENTS OR DIAGNOSTIC AGENTS AND MEDICAMENT CONTAINING THE SAME

The invention relates to pentafluorosulfanyl benzoylguanidines of formula (I), in which R1 to R4 are defined as cited in the claims. Said substances are suitable for use as anti-arrhythmic medicaments comprising cardio-protective components for the prophylaxis and treatment of infarcts, in addition to the treatment of angina pectoris. They also preventatively inhibit the pathophysiological events that occur during ischaemically induced traumas, in particular during the triggering of ischaemically induced cardiac arrhythmia.

ORTHO-SUBSTITUTED PENTAFLUORIDE SULFANYL-BENZENES, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF IN THE FORM OF VALUABLE SYNTHESIS INTERMEDIATE STAGES

The invention relates to pentafluoride-sulfanyl-benzenes of formula (I), wherein groups from R1 to R5 correspond to meanings given in claims and constitute valuable intermediates, for example for producing drugs, diagnosis agents, liquid crystals, polymers, herbicides, fungicidals, nematicidals, parasiticides, insecticides, acaricides and arthropodicides.

A new synthesis of pentafluorosulfanylbenzene

(Equation Presented) A new and convenient three-step synthesis of pentafluorosulfanylbenzene from 1,4-cyclohexadiene with an overall yield of >70% is reported along with a number of derivatization reactions.