852333-48-3

Basic information

• Product Name: 2-methyl-4-(pentafluorosulfanyl)benzenamine
• Synonyms: 2-methyl-4-(pentafluorosulfanyl)benzenamine
• CAS NO: 852333-48-3
• Molecular Weight: 233.205
• Mol File: 852333-48-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-methyl-4-(pentafluorosulfanyl)benzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-4-(pentafluorosulfanyl)benzenamine(852333-48-3)
• EPA Substance Registry System: 2-methyl-4-(pentafluorosulfanyl)benzenamine(852333-48-3)

Safety Data

• Hazardous Substances Data: 852333-48-3(Hazardous Substances Data)

Upstream product

• 823-96-1 Trimethylboroxine 
• 159727-25-0 2-bromo-4-(pentafluoro-λ⁶-sulfanyl)aniline 
• 1411706-57-4 2-methyl-1-nitro-4-(pentafluorosulfanyl)benzene 
• 2993-24-0 4-(pentafluorosulfanyl)aniline 
• 13061-96-6 dihydroxy-methyl-borane 

Relevant articles and documents

Synthesis and properties of pentafluorosulfanyl group (Sf5)-containing meta-diamide insecticides

Herein, we describe novel pentafluorosulfanyl (SF5) group-containing meta-diamide insecticides. For the facile preparation of the SF5-based compounds 4a–d, practical synthetic methods were applied. Among newly synthesized compounds, 3-benzamido-N-(2,6-dimethyl-4-(pentafluoro-λ6-sulfanyl)phenyl)-2-fluorobenzamide 4d showed (i) a high insecticidal activity, (ii) an excellent selectivity to insects, and (iii) good levels of water solubility and log P values. In this study, we demonstrated that the pentafluorosulfanyl moiety could serve as an attractive functionality for the discovery of a new scope of crop-protecting agents.

INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE

Compounds of formula (I') and methods of their use and preparation, as well as compositions comprising compounds of formula (I').

PENTAFLUOROSULFANYL BENZOYLGUANIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE AS MEDICAMENTS OR DIAGNOSTIC AGENTS AND MEDICAMENT CONTAINING THE SAME

The invention relates to pentafluorosulfanyl benzoylguanidines of formula (I), in which R1 to R4 are defined as cited in the claims. Said substances are suitable for use as anti-arrhythmic medicaments comprising cardio-protective components for the prophylaxis and treatment of infarcts, in addition to the treatment of angina pectoris. They also preventatively inhibit the pathophysiological events that occur during ischaemically induced traumas, in particular during the triggering of ischaemically induced cardiac arrhythmia.