159727-71-6Relevant academic research and scientific papers
An Evaluation of the Antirhinoviral Activity of Acylfuran Replacements for 3- Methylisoxazoles. Are 2-Acetylfurans Bioisosteres for 3-Methylisoxazoles?
Bailey, Thomas R.,Diana, Guy D.,Mallamo, John P.,Vescio, Niranjan,Draper, Tandy L.,et al.
, p. 4177 - 4184 (1994)
As a probe of the 3-methylisoxazole portion of our broad-spectrum antipicornaviral series, a panel of 2-acetylfuran analogues was prepared as replacements for the 3-methylisoxazole ring.Comparison of the two series showed remarkable similarity in potency,
