159751-81-2

Upstream product

• 159751-80-1 (R)-2-[(3S,4R,5S,8S)-8-(3-Benzyloxy-phenyl)-8-methoxy-4-methoxymethoxy-3,5-dimethyl-oct-1-ynyl]-3,3,5-trimethyl-6-oxo-cyclohex-1-enecarboxylic acid methyl ester 
• 159751-79-8 (R)-2-[(3S,4R,5S,8S)-8-(3-Benzyloxy-phenyl)-8-methoxy-4-methoxymethoxy-3,5-dimethyl-oct-1-ynyl]-3,3,5-trimethyl-6-oxo-cyclohex-1-enecarboxylic acid 
• 159751-75-4 (2R,8S,9R,10S,13S)-13-(3-Benzyloxy-phenyl)-2-[2-(2,2-dimethoxy-ethyl)-[1,3]dithian-2-yl]-13-methoxy-9-methoxymethoxy-4,4,8,10-tetramethyl-tridec-6-yn-5-one 
• 159751-76-5 (4R,10S,11R,12S,15S)-15-(3-Benzyloxy-phenyl)-1,1,15-trimethoxy-11-methoxymethoxy-4,6,6,10,12-pentamethyl-pentadec-8-yne-3,7-dione 
• 159751-77-6 (R)-2-[(3S,4R,5S,8S)-8-(3-Benzyloxy-phenyl)-8-methoxy-4-methoxymethoxy-3,5-dimethyl-oct-1-ynyl]-3,3,5-trimethyl-6-oxo-cyclohex-1-enecarbaldehyde 
• 159751-67-4 tert-Butyl-{(R)-4-[2-(2,2-dimethoxy-ethyl)-[1,3]dithian-2-yl]-2,2-dimethyl-pentyloxy}-diphenyl-silane 
• 159751-71-0 (4R,5R,6R)-4-[(1S,4S)-4-(3-Benzyloxy-phenyl)-4-methoxy-1-methyl-butyl]-6-chloromethyl-2,2,5-trimethyl-[1,3]dioxane 
• 159751-73-2 1-Benzyloxy-3-((1S,4S,5R,6S)-1-methoxy-5-methoxymethoxy-4,6-dimethyl-oct-7-ynyl)-benzene 
• 159751-66-3 tert-Butyl-((R)-4-[1,3]dithian-2-yl-2,2-dimethyl-pentyloxy)-diphenyl-silane 
• 159751-72-1 (3S,4R,5S,8S)-8-(3-Benzyloxy-phenyl)-8-methoxy-3,5-dimethyl-oct-1-yn-4-ol 
• 159751-62-9 (R)-5-Benzyloxymethoxy-2,2,4-trimethyl-pentanoic acid ethyl ester 
• 159751-69-6 (R)-4-[2-(2,2-Dimethoxy-ethyl)-[1,3]dithian-2-yl]-2,2-dimethyl-pentanal 
• 159751-64-1 (R)-4-[1,3]Dithian-2-yl-2,2-dimethyl-pentanoic acid ethyl ester 
• 159751-68-5 (R)-4-[2-(2,2-Dimethoxy-ethyl)-[1,3]dithian-2-yl]-2,2-dimethyl-pentan-1-ol 

Relevant academic research and scientific papers

Synthetic study on oscillatoxin D: Construction of the C1-C26 spiroether segment by intramolecular aldol condensation and Michael-type addition

The C1-C7 segment (10) and the C8-C21 segment (14) of oscillatoxin D have been synthesized efficiently. The acyclic compound obtained by coupling of these two segments, has been converted into the C1-C26 spiroether (18) possessing the same stereogenic centers of oscillatoxin D. The construction of the spiroether has been achieved by intramolecular aldol condensation and Michael-type addition as key steps.