159801-09-9

Basic information

• Product Name: (2S,3R) methyl 4-<(tert-butyldiphenylsilyl)oxy>-2--3-hydroxybutanoate
• Synonyms: (2S,3R) methyl 4-<(tert-butyldiphenylsilyl)oxy>-2--3-hydroxybutanoate
• CAS NO: 159801-09-9
• Molecular Weight: 602.8
• Mol File: 159801-09-9.mol

Chemical Properties

• CAS DataBase Reference: (2S,3R) methyl 4-<(tert-butyldiphenylsilyl)oxy>-2--3-hydroxybutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R) methyl 4-<(tert-butyldiphenylsilyl)oxy>-2--3-hydroxybutanoate(159801-09-9)
• EPA Substance Registry System: (2S,3R) methyl 4-<(tert-butyldiphenylsilyl)oxy>-2--3-hydroxybutanoate(159801-09-9)

Safety Data

• Hazardous Substances Data: 159801-09-9(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 70681-41-3 (R)-dimethyl malate 

Downstream Products

• 159801-11-3 (2S,3R) benzyl 2--4-<(tert-butyldiphenylsilyl)oxy>-3-hydroxybutanohydroxamate 
• 159801-12-4 (3S,4S) 1-(benzyloxy)-3--4-<(tert-butyldiphenylsilyloxy)methyl>-2-azetidinone 
• 144754-28-9 (3S,4S) 1-(benzyloxy)-3--4-hydroxymethyl-2-azetidinone 

Relevant articles and documents

Enantiospecific and Diastereoselective Synthesis of cis Monobactams through Electrophilic Amination of Chiral 3-Hydroxyesters

A new efficient entry into cis monobactams starting from β-hydroxyesters is reported.This preparation is based on the stereoselective "electrophilic amination" of β-hydroxyester dianions and on Miller's biomimetic synthesis of the β-lactam nucleus.By this route, key intermediates for the preparation of pharmacologically important cis aztreonam 2 and carumonam 3 were prepared.