159847-82-2Relevant academic research and scientific papers
Photoinduced Copper(I)-Catalyzed Cyanation of Aromatic Halides at Room Temperature
Kim, Kicheol,Hong, Soon Hyeok
supporting information, p. 2345 - 2351 (2017/07/22)
The first photoinduced copper(I)-catalyzed cyanation of aromatic halides at room temperature has been developed. The sp2 cyanation reaction exhibits outstanding tolerance to functional groups including primary amines and carboxylic acids, and chemoselectivity to SN2-reactive alkyl chlorides. Mechanistic investigations indicate that the reaction occurs via a single-electron transfer (SET) between the aryl halide and an excited copper(I) cyanide catalytic intermediate. (Figure presented.).
Regioselective Hydrolysis of Aromatic Dinitriles Using a Whole Cell Catalyst
Crosby, John,Moilliet, Jock,Parratt, Julian S.,Turner, Nicolas J.
, p. 1679 - 1688 (2007/10/02)
A series of aromatic dinitriles have been examined as substrates for an immobilised whole cell Rhodococcus sp. that catalyses the hydrolysis of nitriles to amides and/or carboxylic acids.The fluorinated aromatic dinitriles 48 and 49 were regioselectively hydrolysed to the corresponding cyano amides 48a and 49a whereas the non-fluorinated analogues 41-44 were converted to cyano acids but with poorer regioselectivity.
