159885-65-1Relevant academic research and scientific papers
Regioselective cyclocondensation of ethyl 2-ethoxymethylidene-3-oxo-3- polyfluoroalkylpropionates with thiazolylhydrazines
Pryadeina,Denisova,Burgart,Saloutin
experimental part, p. 1811 - 1815 (2009/09/06)
Ethyl 2-ethoxymethylidene-3-oxo-3-polyfluoroalkylpropionates reacted in a regioselective fashion with thiazolylhydrazines to give the corresponding ethyl 1-thiazolyl-5-fluoroalkyl-1H-pyrazole-4-carboxylates. The product structure was determined on the basis of NMR and X-ray diffraction data.
Novel thiazole-based heterocycles as selective inhibitors of fibrinogen- mediated platelet aggregation
Sanfilippo,Urbanski,Beers,Eckardt,Falotico,Ginsberg,Offord,Press,Tighe,Tomko,Andrade-Gordon
, p. 34 - 41 (2007/10/02)
The synthesis and biological activity of novel thiazole-based heterocycles as inhibitors of thrombin-induced human platelet aggregation are described. Further evaluation of selected compounds show they inhibit platelet aggregation as stimulated by a varie
