159897-83-3Relevant academic research and scientific papers
Novel 8-(furan-2-yl)-3-substituted thiazolo [5,4-e][1,2,4] triazolo[1,5-c] pyrimidine-2(3H)-thione derivatives as potential adenosine A2A receptor antagonists
Mishra, Chandra Bhushan,Barodia, Sandeep Kumar,Prakash, Amresh,Senthil Kumar,Luthra, Pratibha Mehta
experimental part, p. 2491 - 2500 (2010/06/20)
Novel thiazolotriazolopyrimidine derivatives (23-33) designed as potential adenosine A2A receptor (A2AR) antagonists were synthesized. Molecular docking studies revealed that all compounds (23-33) exhibited strong interaction with A
Synthesis of novel 7-imino-2-thioxo-3,7-dihydro-2H-thiazolo [4,5-d] pyrimidine derivatives as adenosine A2A receptor antagonists
Luthra, Pratibha Mehta,Mishra, Chandra Bhushan,Jha, Pawan Kumar,Barodia, Sandeep Kumar
experimental part, p. 1214 - 1218 (2010/06/15)
Novel bicyclic thiazolopyrimidine compounds (15-26) were synthesized to develop adenosine A2A receptor (A2AR) antagonist for the treatment of Parkinson's disease (PD). The binding affinity of the compounds (15-26) with A2A
On the Chemistry of 4-Amino-thiazoline-2-thiones II
Gewald, K.,Hain, U.,Schindler, R.,Gruner, M.
, p. 1129 - 1144 (2007/10/02)
6-Amino-thiazoloisothiazole derivatives 4 are obtained by addition of hydrogen sulfide to the 4-Amino-thiazoline-5-carbonitrile 2 followed by cyclooxidation of the intermediate thioamides 3.In the presence of sodium sulfite the hydrolysis of the 4-
