13251-19-9

Basic information

• Product Name: 4-aMino-3-phenyl-2-thioxo-2,3-dihydrothiazole-5-carbonitrile
• Synonyms: 4-aMino-3-phenyl-2-thioxo-2,3-dihydrothiazole-5-carbonitrile;4-amino-3-phenyl-2-sulfanylidene-1,3-thiazole-5-carbonitrile
• CAS NO: 13251-19-9
• Molecular Formula: C₁₀H₇N₃S₂
• Molecular Weight: 233.31268
• Mol File: 13251-19-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 412.3°Cat760mmHg
• Flash Point: 203.1°C
• Appearance: /
• Density: 1.51g/cm³
• Vapor Pressure: 5.24E-07mmHg at 25°C
• Refractive Index: 1.793
• CAS DataBase Reference: 4-aMino-3-phenyl-2-thioxo-2,3-dihydrothiazole-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-aMino-3-phenyl-2-thioxo-2,3-dihydrothiazole-5-carbonitrile(13251-19-9)
• EPA Substance Registry System: 4-aMino-3-phenyl-2-thioxo-2,3-dihydrothiazole-5-carbonitrile(13251-19-9)

Safety Data

• Hazardous Substances Data: 13251-19-9(Hazardous Substances Data)

Usage

General Description

4-Amino-3-phenyl-2-thioxo-2,3-dihydrothiazole-5-carbonitrile is a chemical compound belonging to the class of thiazoles. It is an organic compound with the molecular formula C10H8N4S2. 4-aMino-3-phenyl-2-thioxo-2,3-dihydrothiazole-5-carbonitrile is commonly used in pharmaceutical research and drug development due to its potential biological activities. It has been studied for its antimicrobial and anticancer properties, and it also possesses potential as an anticonvulsant. The compound's unique structure and functional groups make it a promising candidate for the development of new drugs and therapeutic agents.

InChI:InChI=1/C10H7N3S2/c11-6-8-9(12)13(10(14)15-8)7-4-2-1-3-5-7/h1-5H,12H2

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 109-77-3 malononitrile 
• 1885-22-9 bromomalononitrile 
• 1074-52-8 ammonium N-phenyldithiocarbamate 

Downstream Products

• 81402-84-8 4-Amino-2-[(E)-4-methoxy-phenylimino]-3-phenyl-2,3-dihydro-thiazole-5-carbonitrile 
• 81402-99-5 [4-Amino-5-cyano-3-phenyl-3H-thiazol-(2E)-ylidene]-cyano-acetic acid ethyl ester 
• 1454903-76-4 (4E)-4-(4-fluorobenzylideneamino)-3-phenyl-2,3-dihydro-2-thioxothiazole-5-carbonitrile 
• 1454903-85-5 (E)-4-(4-bromobenzylideneamino)-N₃-phenyl-2,3-dihydro-2-thioxothiazole-5-carbonitrile 
• 1454903-80-0 (E)-4-(4-chlorobenzylideneamino)-N₃-phenyl-2,3-dihydro-2-thioxothiazole-5-carbonitrile 
• 159897-52-6 7-amino-3-phenylthiazolo[4,5-d]pyrimidin-2(3H)-thione 

Relevant articles and documents

Design and synthesis of (4E)-4-(4-substitutedbenzylideneamino)-3- substituted-2,3-dihydro-2-thioxothiazole-5-carbonitrile as novel A2A receptor antagonists

Novel 2-thioxothiazole derivatives (6-19) as potential adenosine A 2A receptor (A2AR) antagonists were synthesized. The strong interaction of the compounds (6-19) with A2AR in docking study was confirmed by high binding af

Synthesis of novel 7-imino-2-thioxo-3,7-dihydro-2H-thiazolo [4,5-d] pyrimidine derivatives as adenosine A2A receptor antagonists

Novel bicyclic thiazolopyrimidine compounds (15-26) were synthesized to develop adenosine A2A receptor (A2AR) antagonist for the treatment of Parkinson's disease (PD). The binding affinity of the compounds (15-26) with A2A

Enaminonitrile in Heterocyclic Synthesis: Synthesis of Thiazolopyridine and Thiazolopyrimidine Derivatives

Ammonium N-phenyldithiocarbamate reacted with bromomalononitrile and α-chloroacetylacetone to afford thiazole derivatives 3a, b.Compound 3a reacted with benzylidenemalononitrile, malononitrile, phenylisothiocyanate, benzoylisothiocyanate, trichloroacetonitrile, formamide, carbon disulphide and triethylorthoformate to afford thiazolopyridine derivatives 6, 9 and thiazolopyrimidine derivatives 13, 16, 18, 19, 20 and 21.Most of the synthesized products show high fungicidal and bactericidal activities.