1599480-93-9Relevant academic research and scientific papers
Organocatalyzed asymmetric tandem Michael-cyclization reaction of 4-benzylidene-3-methylpyrazol-5-ones and malononitrile: Stereocontrolled construction of pyrano[2,3-c]pyrazole scaffold
Wang,Wu,Wang,Zhou
, p. 42836 - 42842 (2015)
An efficient approach for the stereocontrolled construction of pyrano[2,3-c]pyrazole scaffold has been developed. Under the catalysis of a bifunctional squaramide derived from (1R,2R)-1,2-diphenylethane-1,2-diamine, the asymmetric tandem Michael addition/
Chiral 1,4-dihydropyrane (2,3-c) pyrazole derivatives and its synthetic method and application
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Paragraph 0038-0039, (2017/02/24)
The invention discloses a chiral 1, 4-dihydropyran (2, 3-c) pyrazole derivative as well as a synthesis method and application of the chiral 1, 4-dihydropyran (2, 3-c) pyrazole derivative. The synthesis method comprises the steps of with methylbenzene as a
Enantioselective synthesis of functionalized fluorinated dihydropyrano [2,3-c]pyrazoles catalyzed by a simple bifunctional diaminocyclohexane-thiourea
Zhang, Hong-Fei,Ye, Zheng-Qing,Zhao, Gang
supporting information, p. 535 - 540 (2014/05/06)
Enantioselective synthesis of functionalized fluorinated dihydropyrano[2,3-c]pyrazoles has been achieved via a diaminocyclohexane- thiourea catalyzed cascade Michael addition and Thorpe-Ziegler type cyclization in high yields (up to 98%) with moderate to good enantioselectivity (up to 90% ee).
