159949-24-3

Upstream product

• 32780-06-6 (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran 

Downstream Products

• 280783-56-4 Ro 64-6198 
• 280783-56-4 8-(2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one 
• 309254-86-2 (1R,3aS)-1-(2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl)-4-phenylamino-piperidine-4-carbonitrile 
• 309254-78-2 (1S,3aS)-1-(2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl)-4-phenylamino-piperidine-4-carbonitrile 

Relevant academic research and scientific papers

A synthetic approach to the pseudopterosins using cascade technology

A rapid synthetic entry towards the pseudopterosins, a class of diterpenes which display potent anti-inflammatory and analgesic properties, is described. The key feature of this approach is the use of a sequential intramolecular, Lewis acid mediated Friedel-Crafts alkylation - Friedel-Crafts acylation sequence, viz 14 to 15, to establish the tricyclic carbon framework.