159979-58-5Relevant academic research and scientific papers
Pancreatic anticancer activity of a novel geranylgeranylated coumarin derivative
Devji, Tehsina,Reddy, Claire,Woo, Christina,Awale, Suresh,Kadota, Shigetoshi,Carrico-Moniz, Dora
, p. 5770 - 5773 (2011)
A series of hydroxycoumarin derivatives has been synthesized and evaluated against human pancreatic PANC-1 cancer cells under nutrient-deprived conditions. Several compounds exhibited 100% preferential cytotoxicity at low micromolar concentrations under n
Natural Product Chemistry. Part 181. Investigations on the Synthesis of Dihydropyrano- and Dihydrofurano-coumarins by Application of Catalytic Enantioselective cis-Dihydroxylation
Reisch, Johannes,Voerste, Arnd A. W.
, p. 3251 - 3256 (2007/10/02)
As part of a study on the applicability of catalytic enantioselective cis-dihydroxylation for the synthesis of dihydropyrano- and dihydrofurano-anellated coumarins new routes to (-)-cis-khellactone 1b, (-)-trans-khellactone 1c and rutaretin 4 have been developed.
