160002-04-0Relevant articles and documents
6-Azasteroids: Structure-Activity Relationships for Inhibition of Type 1 and 2 Human 5α-Reductase and Human Adrenal 3β-Hydroxy-Δ5-steroid Dehydrogenase/3-Keto-Δ5-steroid Isomerase
Frye, Stephen V.,Haffner, Curt D.,Maloney, Patrick R.,Mook, Robert A.,Dorsey, George F.,et al.
, p. 2352 - 2360 (1994)
6-Azaandrost-4-en-3-ones were synthesized and tested versus human type 1 and 2 steroid 5α-reductase (5AR) and human adrenal 3β-hydroxy-Δ5-steroid dehydrogenase/3-keto-Δ5-steroid isomerase (3BHSD) to explore the structure-activity rel