160012-10-2Relevant academic research and scientific papers
Catalytic asymmetric Michael addition of nitroalkane to enone and enal
Yamaguchi, Masahiko,Shiraishi, Tai,Igarashi, Yoshihiro,Hirama, Masahiro
, p. 8233 - 8236 (1994)
L-Proline rubidium salt catalyzes the asymmetric Michael addition of nitroalkanes to enones and an enal. (R)-Adducts were obtained from cyclic (Z)-enones and (S)-adducts from acyclic (E)-enones, Bu3SnH treatment of the products replaced the nit
Catalytic asymmetric conjugate addition of nitroalkanes to cycloalkenones
Hanessian, Stephen,Pham, Vinh
, p. 2975 - 2978 (2000)
Nitroalkanes add to cyclic and acyclic enones in an enantioselective manner in the presence of catalytic quantities of L-proline and trans2,5-dimethylpiperazine as excess additive.
Optimization of the catalytic asymmetric addition of nitroalkanes to cyclic enones with trans-4,5-methano-L-proline
Hanessian, Stephen,Shao, Zhihui,Warrier, Jayakumar S.
, p. 4787 - 4790 (2007/10/03)
(Chemical Equation Presented) The conjugate addition of symmetrical 2-nitroalkanes to 2-cycloalkenones catalyzed by trans-4,5-methano-L-proline proceeds with >99% ee and excellent chemical yields. 1-Nitroalkanes afford diastereomeric syn/anti products tha
