160024-47-5

Upstream product

• 1569-94-4 (3-phenyl-4,5-dihydro-isoxazol-5-yl)-methanol 
• 74-88-4 methyl iodide 
• 932-90-1 Benzaldoxime 
• 119897-89-1 (R)-3-phenyl-Δ²-isoxazoline-5-methanol 

Downstream Products

• 119897-89-1 (R)-3-phenyl-Δ²-isoxazoline-5-methanol 
• 159974-70-6 (2R,4R)-4-phenyl-1,2,4-butanetriol 
• 159974-68-2 (R)-3,4-dihydroxy-1-phenylbutan-1-one 

Relevant academic research and scientific papers

Highly Stereoselective [3+2] Cycloadditions of Nitrile Oxides to Methyl 4-O-Acryloyl-6-deoxy-2,3-O-(t-butyldimethylsilyl)-α-D-glucopyranoside

The [3+2] cycloadditions of benzonitrile oxide or pivalonitrile oxide to methyl 4-O-acryloyl-6-deoxy-2,3-di-O-(t-butyldimethylsilyl)-α -D-glucopyranoside provided the respective adducts, each as virtually a single diastereomer. By reductive removal of the

Synthesis of a bifunctional 2,4-dihydroxy five-carbon synthon. Enantiomerically pure Δ2-isoxazolines by chromatographic resolution

Chromatography on cellulose triacetate allows the separation of (R)- and (S)-4,5-dihydro-3-phenyl-5-isoxazolemethanol in 100% ee. Reductive ring cleavage, diastereoselective reduction of the 3-hydroxy ketones thus obtained, and oxidation of the phenyl rin