1600526-68-8Relevant academic research and scientific papers
Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes
Filosa, Rosanna,Peduto, Antonella,Schaible, Anja M.,Krauth, Verena,Weinigel, Christina,Barz, Dagmar,Petronzi, Carmen,Bruno, Ferdinando,Roviezzo, Fiorentina,Spaziano, Giuseppe,D'Agostino, Bruno,De Rosa, Mario,Werz, Oliver
supporting information, p. 132 - 139 (2015/04/14)
5-Lipoxygenase (5-LO) is a potential target for pharmacological intervention with various inflammatory and allergic diseases. Starting from the natural dual 5-LO/microsomal prostaglandin E2 synthase (mPGES)-1 inhibitor embelin (2,5-dihydroxy-3-
MULTIFUNCTIONAL RADICAL QUENCHERS
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Page/Page column 68-69, (2014/05/07)
The invention provides a compound of formula (I): [insert formula (I)] wherein X, Y, and R1-R4 have any of the values defined in the specification, and salts thereof, as well as compositions comprising the compounds or salts. The compounds are useful for treating diseases associated with impaired mitochondrial function in an animal.
