1600528-08-2Relevant academic research and scientific papers
Design, synthesis, and biological activity of NCC149 derivatives as histone deacetylasea 8-selective inhibitors
Suzuki, Takayoshi,Muto, Nobusuke,Bando, Masashige,Itoh, Yukihiro,Masaki, Ayako,Ri, Masaki,Ota, Yosuke,Nakagawa, Hidehiko,Iida, Shinsuke,Shirahige, Katsuhiko,Miyata, Naoki
, p. 657 - 664 (2014/03/21)
We recently discovered N-hydroxy-3-[1-(phenylthio)methyl-1H-1,2,3-triazol- 4-yl]benzamide (NCC149) as a potent and selective histone deacetylasea 8 (HDAC8) inhibitor from a 151-member triazole compound library using a click chemistry approach. In this wor
