1600528-61-7Relevant academic research and scientific papers
Synthesis of novel curcumin analogues for inhibition of 11β-hydroxysteroid dehydrogenase type 1 with anti-diabetic properties
Yuan, Xiaohuan,Li, Hongzhi,Bai, He,Su, Zhijian,Xiang, Qi,Wang, Chaonan,Zhao, Binghai,Zhang, Yufei,Zhang, Qihao,Chu, Yanhui,Huang, Yadong
, p. 223 - 230 (2014/04/03)
In the present study, a series of mono-carbonyl analogues of curcumin were designed and synthesized by deleting the reactive beta-diketone moiety, which is responsible for the pharmacokinetic limitation of curcumin. We demonstrated that 4 of 9 curcumin an
