160084-16-2

Upstream product

• 38611-22-2 2,3-dibromo-5-trimethylsilylfuran 
• 36772-04-0 1-(3-Butynyl)-2,6,6-trimethyl-1-cyclohexene 
• 119987-27-8 2-trimethylsilyl-4-bromofuran 
• 94742-51-5 5-trimethylsilyl-3-furoic acid 
• 160084-13-9 (2E,6E)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-7-methyl-3-<(tert-butyldimethylsilyloxy)methyl>-1-(N,N-di-n-butylamino)-2,6-nonadiene 
• 160084-07-1 Phosphoric acid diethyl ester 1-methylene-3-(2,6,6-trimethyl-cyclohex-1-enyl)-propyl ester 
• 17283-81-7 4-(2,6,6-Trimethyl-cyclohex-1-enyl)-butan-2-on 
• 58832-36-3 5-bromofuran-3-carboxylic acid 
• 488-93-7 3-Furoic acid 
• 160084-06-0 2-trimethylsilyl-4-(1,3-dithian-2-yl)-furan 
• 160084-14-0 tert-Butyl-[(E)-2-[2-chloro-eth-(E)-ylidene]-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-oct-5-enyloxy]-dimethyl-silane 
• 160084-12-8 (2E,6E)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-7-methyl-3-hydroxymethyl-1-(N,N-di-n-butylamino)-2,6-nonadiene 
• 110202-09-0 1-bromo-4-methyl-6-(2,6,6-trimethylcyclohex-1-enyl)-3-hexene 
• 110202-07-8 (E)-4-Methyl-6-(2',6',6'-trimethyl-1'-cyclohexenyl)hex-3-en-1-ol 

Downstream Products

• 160084-18-4 2-trimethylsilyl-4-<(2E,6E)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-7-methyl-4-hydroxymethyl-1-hydroxy-2,6-nonadien-1-yl>-furan 
• 110202-12-5 2-trimethylsilyl-4-<(3E,7E)-10-(2,6,6-trimethyl-1-cyclohexen-1-yl)-8-methyl-4-formyl-1-hydroxy-3,7-decadien-1-yl>-furan 

Relevant academic research and scientific papers

Two Syntheses of Manoalide via Heteroatom-Assisted Alkyne Carbometallation

Two approaches to the sesterterpenoid phospholipase A2 inhibitors seco-manoalide (3) and manoalide (1) are described based on carbometallation of propargylic alcohols to generate the functionalised C6-C7 trisubstituted alkene.Both syntheses also deploy the photooxidation of a furan in order to generate a 4-substituted 5-hydroxy-2(5H)-furanone moiety.