16012-26-3Relevant academic research and scientific papers
Xanthine oxidase inhibitory activity of nicotino/isonicotinohydrazides: A systematic approach from in vitro, in silico to in vivo studies
Zafar, Humaira,Hayat, Muhammad,Saied, Sumayya,Khan, Momin,Salar, Uzma,Malik, Rizwana,Choudhary, M. Iqbal,Khan, Khalid Mohammed
, p. 2351 - 2371 (2017/04/03)
Change in life style and eating habits has led to an increased prevalence of hyperuricemia worldwide. The role of hyperuricemia is no more restricted to gout, but it has a central role in progression of CVD, hypertension, metabolic syndrome, and arthritis
Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto-5′-nucleotidase
Channar, Pervaiz Ali,Shah, Syed Jawad Ali,Hassan, Sidra,Nisa, Zaib un,Lecka, Joanna,Sévigny, Jean,Bajorath, Jürgen,Saeed, Aamer,Iqbal, Jamshed
, p. 365 - 370 (2017/04/03)
A series of isonicotinohydrazide derivatives was synthesized and tested against recombinant human and rat ecto-5′-nucleotidases (h-e5′NT and r-e5′NT) and alkaline phosphatase isozymes including both bovine tissue-non-specific alkaline phosphatase (b-TNAP)
Synthesis, characterization and pharmacological evaluation of (E)-N′-(substituted-benzylidene)isonicotinohydrazide derivatives as potent anticonvulsant agents
Malhotra, Manav,Monga, Vikramdeep,Sharma, Sagun,Jain, Jainendra,Samad, Abdul,Stables, James,Deep, Aakash
, p. 2145 - 2152 (2012/11/07)
A series of (E)-N′-(substituted-benzylidene)isonicotinohydrazide derivatives were synthesized by coupling it with different substituted aldehydes, acetophenone, and benzophenones in presence of absolute ethanol along with catalytic amount of glacial aceti
Synthesis and anti-mycobacterial activity of (E)-N′-(monosubstituted-benzylidene)isonicotinohydrazide derivatives
Lourenco, Maria Cristina da Silva,Ferreira, Marcelle de Lima,de Souza, Marcus Vinicius Nora,Peralta, Monica Amado,Vasconcelos, Thatyana Rocha Alves,Henriques, Maria das Gracas M.O.
, p. 1344 - 1347 (2008/09/21)
A series of 22 (E)-N′-(monosubstituted-benzylidene)isonicotinohydrazide derivatives have been synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv using Alamar Blue susceptibility test and
Four nitrobenzaldehyde isonicotinoyl-hydrazones at 120 K: Four different supramolecular structures in two and three dimensions
Wardell, Solange M. S. V.,De Souza, Marcus V. N.,Wardell, James L.,Low, John N.,Glidewell, Christopher
, p. o683-o689 (2007/10/03)
The molecules of 2-nitrobenzaldehyde isonicotinoylhydra-zone, C 13H10N4O3, (I), are linked into a three-dimensional framework by a combination of one N-H...N and three C-H...O hydrogen bonds. In the isomeric com
