160133-79-9

Basic information

• Product Name: 3-AMINO-4-METHYL-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
• Synonyms: 3-AMINO-4-METHYL-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER;Methyl 3-amino-4-methyl-5-phenyl-2-thiophenecarboxylate
• CAS NO: 160133-79-9
• Molecular Formula: C₁₃H₁₃NO₂S
• Molecular Weight: 247.31
• Mol File: 160133-79-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 430.0±45.0 °C(Predicted)
• Appearance: /
• Density: 1.232±0.06 g/cm3(Predicted)
• PKA: 1.55±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-4-METHYL-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-4-METHYL-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER(160133-79-9)
• EPA Substance Registry System: 3-AMINO-4-METHYL-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER(160133-79-9)

Safety Data

• Hazardous Substances Data: 160133-79-9(Hazardous Substances Data)

Upstream product

• 2365-48-2 Methyl thioglycolate 
• 474543-00-5 (Z)-3-Chloro-2-methyl-3-phenyl-acrylonitrile 
• 35811-93-9 3-chloro-2-methylcinnamaldehyde 
• 1078789-34-0 methyl 3-amino-5-bromo-4-methylthiophene-2-carboxylate 
• 98-80-6 phenylboronic acid 
• 17763-67-6 Phenyl triflate 
• 85006-31-1 3-amino-4-methyl-2-thiophenecarboxylic acid methyl ester 
• 108-86-1 bromobenzene 

Downstream Products

• 474543-10-7 3-methyl-5,8-dioxo-2-phenyl-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine-7-carboxylic acid methyl ester 
• 474543-16-3 3-methyl-2-phenyl-6,7-dihydro-4H-thieno[3,2-b]azepine-5,8-dione 
• 474543-04-9 3-(3-methoxycarbonylpropionylamino)-4-methyl-5-phenylthiophene-2-carboxylic acid methyl ester 

Relevant articles and documents

EIF4E INHIBITORS AND USES THEREOF

The present invention provides compounds inhibiting elF4E activity and compositions and methods of using thereof.

Synthesis of new thieno[b]azepinediones from α-methylene ketones

New substituted 6,7-dihydro-4H-thieno[3,2-b]azepine-5,8-diones were synthesized in seven steps, starting from substituted α-methylene ketones, via 3-aminothiophene-2-carboxylic acid alkyl esters.