1601460-53-0

Upstream product

• 869732-13-8 3-(benzyloxy)-5-bromo-2-methoxybenzaldehyde 

Downstream Products

• 1601460-57-4 (2S,4R)-5-(3-(benzyloxy)-5-bromo-2-methoxyphenyl)-1-((tert-butyldimethylsilyl)oxy)-4-methylpentan-2-ol 
• 1601460-58-5 (((2S,4R)-5-(3-(benzyloxy)-5-bromo-2-methoxyphenyl)-2-methoxy-4-methylpentyl)oxy)(tert-butyl)dimethylsilane 
• 1601460-59-6 (2S,4R)-5-(3-(benzyloxy)-5-bromo-2-methoxyphenyl)-2-methoxy-4-methylpentan-1-ol 
• 869732-16-1 (2S,4R)-5-(3-(benzyloxy)-5-bromo-2-methoxyphenyl)-2-methoxy-4-methylpentanal 
• 1601460-60-9 (4S,5R,6S,8R)-9-(3-(benzyloxy)-5-bromo-2-methoxyphenyl)-6-methoxy-4,8-dimethylnon-2-yn-5-ol 
• 869732-10-5 1-(benzyloxy)-5-bromo-2-methoxy-3-((2R,4S,5R,6S)-4-methoxy-5-(methoxymethoxy)-2,6-dimethylnon-7-yn-1-yl)benzene 
• 1601460-51-8 1-(benzyloxy)-5-bromo-3-(bromomethyl)-2-methoxybenzene 
• 869732-18-3 (2E,6S,7S,8E,10S,11R,12S,14R)-ethyl 15-(3-(benzyloxy)-5-bromo-2-methoxyphenyl)-7-hydroxy-6,12-dimethoxy-11-(methoxymethoxy)-2,8,10,14-tetramethylpentadeca-2,8-dienoate 
• 1601460-66-5 C₂₈H₃₉BrO₅ 
• 869732-32-1 (2E,6S,7S,8E,10S,11R,12S,14R)-ethyl 15-(3-(benzyloxy)-5-bromo-2-methoxyphenyl)-7-((tert-butyldimethylsilyl)oxy)-6,12-dimethoxy-11-(methoxymethoxy)-2,8,10,14-tetramethylpentadeca-2,8-dienoate 
• 869732-33-2 (2E,6S,7S,8E,10S,11R,12S,14R)-15-(3-(benzyloxy)-5-bromo-2-methoxyphenyl)-7-((tert-butyldimethylsilyl)oxy)-6,12-dimethoxy-11-(methoxymethoxy)-2,8,10,14-tetramethylpentadeca-2,8-dienoic acid 
• 869732-09-2 (2E,6S,7S,8E,10S,11R,12S,14R)-15-(3-(benzyloxy)-5-bromo-2-methoxyphenyl)-7-((tert-butyldimethylsilyl)oxy)-6,12-dimethoxy-11-(methoxymethoxy)-2,8,10,14-tetramethylpentadeca-2,8-dienamide 
• 869732-19-4 (4E,8S,9S,10E,12S,13R,14S,16R)-20-(benzyloxy)-9-(tertbutyldimethylsilyloxy)-13-(methoxymethoxy)-4,10,12,16-tetramethyl-,14,19-trimethoxy-2-azabicyclo[16.3.1]docosa-1⁽²¹⁾,4,10,18⁽²²⁾,19-pentaen-3-one 
• 869732-34-3 (4E,8S,9S,10E,12S,13R,14S,16R)-20-(benzyloxy)-9-hydroxy-13-(methoxymethoxy)-4,10,12,16-tetramethyl-14,19-trimethoxy-2-azabicyclo[16.3.1]docosa-1⁽²¹⁾,4,10,18⁽²²⁾,19-pentaen-3-one 

Relevant academic research and scientific papers

Total synthesis of reblastatin: Convenient preparation of coupling partners and scaled assembly

Potentially scalable total synthesis of reblastatin was achieved based on Panek's previous study. Novel and convenient synthetic routes were developed for the known C8-C20 and C1-C7 coupling partners. The challenging C8-C20 fragment was prepared from TBS