160147-88-6

Basic information

• Product Name: methyl 2-benzyloxycarbonylamino-2-deoxy-3,4-O-isopropylidene-D-mannonate
• Synonyms: methyl 2-benzyloxycarbonylamino-2-deoxy-3,4-O-isopropylidene-D-mannonate
• CAS NO: 160147-88-6
• Molecular Weight: 383.398
• Mol File: 160147-88-6.mol

Chemical Properties

• CAS DataBase Reference: methyl 2-benzyloxycarbonylamino-2-deoxy-3,4-O-isopropylidene-D-mannonate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-benzyloxycarbonylamino-2-deoxy-3,4-O-isopropylidene-D-mannonate(160147-88-6)
• EPA Substance Registry System: methyl 2-benzyloxycarbonylamino-2-deoxy-3,4-O-isopropylidene-D-mannonate(160147-88-6)

Safety Data

• Hazardous Substances Data: 160147-88-6(Hazardous Substances Data)

Upstream product

• 133473-08-2 methyl 3,4;5,6-di-O-isopropylidene-2-amino-2-deoxy-D-mannate 
• 117462-55-2 methyl 2-azido-2-deoxy-3,4:5,6-di-O-isopropylidene-D-mannonate 
• 160147-87-5 methyl 2-benzyloxycarbonylamino-2-deoxy-3,4:5,6-di-O-isopropylidene-D-mannonate 

Downstream Products

• 160147-89-7 methyl 2-benzyloxycarbonylamino-2-deoxy-3,4-O-isopropylidene-6-O-methanesulfonyloxy-D-mannonate 
• 161867-54-5 (S)-Benzyloxycarbonylamino-{(4R,5R)-5-[(R)-2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-acetic acid methyl ester 
• 161867-56-7 Methanesulfonic acid (R)-1-[(4S,5R)-5-((R)-1-benzyloxycarbonylamino-2-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-2-(tert-butyl-dimethyl-silanyloxy)-ethyl ester 
• 161867-55-6 (S)-Benzyloxycarbonylamino-{(4R,5S)-5-[(R)-2-(tert-butyl-dimethyl-silanyloxy)-1-methanesulfonyloxy-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-acetic acid methyl ester 
• 14199-63-4 1-deoxymannojirimycin 
• 113000-77-4 (2S,3R,4R,5R)-3,4,5-trihydroxypipecolic acid 

Relevant articles and documents

Efficient cleavage of terminal acetonide group: Chirospecific synthesis of 2,5-Dideoxy-2,5-Imino-D-Mannitol

Dowex 50W-X8 was efficient catalyst for selective cleavage of terminal actonide including acid-sensitive multifunctional groups. A facile and economically synthesis of DMDP (2,5-dideoxy-2,5-imino-D-mannitol) is described via selective hydrolysis and intramolecular nucleophilic amination.

Simple Synthesis of (-)-Deoxymannojirimycin and (2S,3R,4R,5R)-3,4,5-trihydroxypipecolic Acid via Regioselective Hydrolysis

A short and efficient synthesis of (-)-deoxymannojirimycin and (2S,3R,4R,5R)-3,4,5-trihydroxypipecolic acid is described with D-glucono-δ-lactone as chiral educt.Key transformations included selective cleavage of a terminal isopropylidene group with Dowex 50W-X8 (H+) and intramolecular nucleophilic amination.