160147-89-7Relevant articles and documents
Simple Synthesis of (-)-Deoxymannojirimycin and (2S,3R,4R,5R)-3,4,5-trihydroxypipecolic Acid via Regioselective Hydrolysis
Park, Ki Hun,Yoon, Yong Jin,Lee, Sang Gyeong
, p. 2621 - 2624 (2007/10/02)
A short and efficient synthesis of (-)-deoxymannojirimycin and (2S,3R,4R,5R)-3,4,5-trihydroxypipecolic acid is described with D-glucono-δ-lactone as chiral educt.Key transformations included selective cleavage of a terminal isopropylidene group with Dowex 50W-X8 (H+) and intramolecular nucleophilic amination.