1601476-24-7Relevant academic research and scientific papers
Substituted piperidines as HDM2 inhibitors
Ma, Yao,Lahue, Brian R.,Shipps Jr., Gerald W.,Brookes, Jeseca,Wang, Yaolin
, p. 1026 - 1030 (2014)
Novel small molecule HDM2 inhibitor, substituted piperidine, was identified. Initial SAR study indicated potential for several position optimizations. Additional potency enhancement was achieved by introducing a sidechain off the aromatic ring. DMPK study
