160168-19-4

Basic information

• Product Name: BOC-3-(4'methoxycarbonyl)-L-alanine mesthyl ester
• Synonyms: BOC-3-(4'methoxycarbonyl)-L-alanine mesthyl ester;L-PHENYLALANINE, N-[(1,1-DIMETHYLETHOXY)CARBONYL]-4-(METHOXYCARBONYL)-, METHYL ESTER;(S)-methyl 4-(2-(tert-butoxycarbonylamino)-3-methoxy-3-oxopropyl)benzoate
• CAS NO: 160168-19-4
• Molecular Formula: C₁₇H₂₃NO₆
• Molecular Weight: 337.37
• Mol File: 160168-19-4.mol

Chemical Properties

• Melting Point: 82-83 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 464.0±45.0 °C(Predicted)
• Appearance: /
• Density: 1.155±0.06 g/cm3(Predicted)
• PKA: 10.88±0.46(Predicted)
• CAS DataBase Reference: BOC-3-(4'methoxycarbonyl)-L-alanine mesthyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-3-(4'methoxycarbonyl)-L-alanine mesthyl ester(160168-19-4)
• EPA Substance Registry System: BOC-3-(4'methoxycarbonyl)-L-alanine mesthyl ester(160168-19-4)

Safety Data

• Hazardous Substances Data: 160168-19-4(Hazardous Substances Data)

Upstream product

• 619-44-3 methyl 4-iodobenzoate 
• 93267-04-0 N-(tert-butoxycarbonyl)-L-3-iodoalanine methyl ester 
• 69942-12-7 N-tert-butoxycarbonylserine methyl ester 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 175844-11-8 methyl (2R)-2-[(tert-butoxycarbonyl)amino]-3-bromopropionate 
• 5042-77-3 p-toluenesulfonic acid salt of L-serine 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 112766-18-4 methyl N-(tert-butoxycarbonyl)-O-[(trifluoromethyl)sulfonyl]-L-tyrosinate 

Downstream Products

• 160063-50-3 4-(carboxy)-N-<(1,1-dimethylethoxy)carbonyl>-L-phenylalanine 
• 160063-51-4 4-<(cyclohexyloxy)carbonyl>-N-<(1,1-dimethylethoxy)carbonyl>-L-phenylalanine, cyclohexyl ester 

Relevant articles and documents

Synthesis of Enantiopure Unnatural Amino Acids by Metallaphotoredox Catalysis

We describe herein a two-step process for the conversion of serine to a wide array of optically pure unnatural amino acids. This method utilizes a photocatalytic cross-electrophile coupling between a bromoalkyl intermediate and a diverse set of aryl halides to produce artificial analogues of phenylalanine, tryptophan, and histidine. The reaction is tolerant of a broad range of functionalities and can be leveraged toward the scalable synthesis of valuable pharmaceutical scaffolds via flow technology.