16019-31-1

Basic information

• Product Name: 5-ALLYL-4,6-DICHLORO-PYRIMIDINE
• Synonyms: 5-ALLYL-4,6-DICHLORO-PYRIMIDINE;4,6-dichloro-5-(prop-2-en-1-yl)pyriMidine;PyriMidine, 4,6-dichloro-5-(2-propen-1-yl)-;4,6-dichloro-5-(2-propen-1-yl)Pyrimidine
• CAS NO: 16019-31-1
• Molecular Formula: C₇H₆Cl₂N₂
• Molecular Weight: 189.05
• Mol File: 16019-31-1.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 261℃
• Flash Point: 137℃
• Appearance: /
• Density: 1.31
• Vapor Pressure: 0.0193mmHg at 25°C
• Refractive Index: 1.552
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 5-ALLYL-4,6-DICHLORO-PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ALLYL-4,6-DICHLORO-PYRIMIDINE(16019-31-1)
• EPA Substance Registry System: 5-ALLYL-4,6-DICHLORO-PYRIMIDINE(16019-31-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 16019-31-1(Hazardous Substances Data)

Usage

Chemical Properties

Pale yellow paint, liquid

InChI:InChI=1/C7H6Cl2N2/c1-2-3-5-6(8)10-4-11-7(5)9/h2,4H,1,3H2

Upstream product

• 1193-21-1 4,6-dichloropyrimidine 
• 106-95-6 allyl bromide 
• 40637-56-7 dimethyl allylmalonate 
• 16019-30-0 5-allyl-6-hydroxy-3H-pyrimidin-4-one 
• 16019-30-0 6-hydroxy-5-(2-propen-1-yl)-4(1H)-pyrimidinone 
• 16019-30-0 5-(prop-2-en-1-yl)pyrimidine-4,6-diol 
• 1426659-18-8 5-(4,6-dichloropyrimidinyl)zinc pivalate 
• 2049-80-1 (2-propenyl)propanedioic acid diethyl ester 

Downstream Products

• 1001397-65-4 4-bromo-N-[2-(4,6-dichloro-5-pyrimidinyl)ethyl]-2,5-difluoroaniline 
• 1001397-58-5 4-{[6-chloro-5-(2-propen-1-yl)-4-pyrimidinyl]amino}-2,5-difluorobenzonitrile 
• 14052-82-5 4,6-dichloro-5-(2,2-diethoxyethyl)pyrimidine 

Relevant articles and documents

An improved synthesis of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine

[Figure not available: see fulltext.] An improved seven-step synthesis of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine from dimethyl malonate with 31% overall yield is described. The procedure is operationally simple and practical for the synthesis of the 4-chloro-7H-pyrrolo[2,3-d]pyrimidine building block.

Exploiting Atropisomerism to Increase the Target Selectivity of Kinase Inhibitors

Many biologically active molecules exist as rapidly interconverting atropisomeric mixtures. Whereas one atropisomer inhibits the desired target, the other can lead to off-target effects. Herein, we study atropisomerism as a possibility to improve the sele

CYCLOLIC HYDRAZINE DERIVATIVES AS HIV ATTACHMENT INHIBITORS

Compounds of Formula I are provided, including pharmaceutically acceptable salts thereof: wherein A is selected from the group consisting of: wherein Z is selected from the group consisting of: which are useful as HIV attachment inhibitors.