16019-30-0

Usage

Uses

Used in Pharmaceutical Synthesis:
5-allylpyrimidine-4,6-diol is used as a building block for the synthesis of pharmaceuticals. Its unique structure and reactivity allow for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 5-allylpyrimidine-4,6-diol serves as a key component in the synthesis of various agrochemicals. Its incorporation into these compounds can enhance their effectiveness in agricultural applications.
Used in Organic Chemistry Research:
5-allylpyrimidine-4,6-diol is utilized in organic chemistry research for studying the properties and reactions of pyrimidine derivatives. Its presence in various chemical reactions provides insights into the behavior of similar compounds.
Used in Nucleoside and Nucleotide Preparation:
5-allylpyrimidine-4,6-diol is used in the preparation of nucleosides and nucleotides, which are essential components of genetic material. These molecules play a crucial role in biological processes, making 5-allylpyriMidine-4,6-diol important for understanding and manipulating genetic information.
Overall, 5-allylpyrimidine-4,6-diol is a versatile compound with applications in various industries, including pharmaceuticals, agrochemicals, organic chemistry research, and the preparation of genetic material components. Its unique structure and reactivity contribute to its significance in these fields.

InChI:InChI=1/C7H8N2O2/c1-2-3-5-6(10)8-4-9-7(5)11/h2,4H,1,3H2,(H2,8,9,10,11)

Upstream product

• 2049-80-1 (2-propenyl)propanedioic acid diethyl ester 
• 463-52-5 formamidine 
• 6313-33-3 formamidine hydrochloride 
• 40637-56-7 dimethyl allylmalonate 
• 77287-34-4 formamide 
• 3473-63-0 formamidine acetic acid 

Downstream Products

• 16019-31-1 5-allyl-4,6-dichloropyrimidine 
• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 
• 1456534-50-1 5-phenyl-1,2,3,4-tetrahydropyridazino[3,4-d]pyrimidine 
• 1456534-49-8 4-chloro-5-(2-chloroethyl)-6-phenylpyrimidine 
• 1456534-48-7 2-(4-chloro-6-phenylpyrimidin-5-yl)ethanol 
• 1456534-47-6 2-(4-chloro-6-phenylpyrimidin-5-yl)acetaldehyde 
• 1456534-46-5 4-chloro-5-(2,2-diethoxyethyl)-6-phenylpyrimidine 
• 1456534-31-8 1-(4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-(5-phenyl-3,4-dihydropyrimido[4,5-c]pyridazin-2(1H)-yl)ethane-1,2-dione 
• 1456534-45-4 1,3-dimethyl-5-phenyl-1,2,3,4-tetrahydropyridazino[3,4-d]pyrimidine 
• 1456534-44-3 1,3-dimethyl-5-phenyl-1,4-dihydropyridazino[3,4-d]pyrimidine 
• 1456534-30-7 1-(1,3-dimethyl-5-phenyl-3,4-dihydropyrimido[4,5-c]pyridazin-2(1H)-yl)-2-(4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione 
• 1456534-38-5 1-methyl-5-phenyl-1,2,3,4-tetrahydropyrimido[4,5-c]pyridazine 
• 1456534-37-4 1-methyl-5-phenyl-1,4-dihydropyrimido[4,5-c]pyridazine 
• 1456534-36-3 5-chloro-1-methyl-1,4-dihydropyridazino[3,4-d]pyrimidine 

Relevant academic research and scientific papers

An improved synthesis of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine

[Figure not available: see fulltext.] An improved seven-step synthesis of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine from dimethyl malonate with 31% overall yield is described. The procedure is operationally simple and practical for the synthesis of the 4-chloro-7H-pyrrolo[2,3-d]pyrimidine building block.

ATROPISOMERISM FOR ENHANCED KINASE INHIBITOR SELECTIVITY

The invention provides a series of conformationally stable and selective kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly inter

Exploiting Atropisomerism to Increase the Target Selectivity of Kinase Inhibitors

Many biologically active molecules exist as rapidly interconverting atropisomeric mixtures. Whereas one atropisomer inhibits the desired target, the other can lead to off-target effects. Herein, we study atropisomerism as a possibility to improve the sele

CYCLOLIC HYDRAZINE DERIVATIVES AS HIV ATTACHMENT INHIBITORS

Compounds of Formula I are provided, including pharmaceutically acceptable salts thereof: wherein A is selected from the group consisting of: wherein Z is selected from the group consisting of: which are useful as HIV attachment inhibitors.

Discovery of 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines as orally available g protein-coupled receptor 119 agonists

GPR119 is a 7-transmembrane receptor that is expressed in the enteroendocrine cells in the intestine and in the islets of Langerhans in the pancreas. Indolines and 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines were discovered as G protein-coupled receptor 119

FUSED BICYCLIC PYRIMIDINE DERIVATIVES AND METHODS OF USE THEREOF

The present invention relates to Fused Bicyclic Pyrimidine Derivatives, compositions comprising a Fused Bicyclic Pyrimidine Derivative, and methods of using the Fused Bicyclic Pyrimidine Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of a G-protein coupled receptor (GPCR) in a patient.

AZAINDOLE P2X3 AND P2X2/3 MODULATORS

The application discloses compounds of the Formula I: or a pharmaceutically acceptable salt thereof, wherein, X, R1, R2 R3, R4, R5, R6, R7 and R8 are as defined herein. Also provided are methods of using the compounds for treating diseases associated with the P2X3 and/or a P2X2/3 receptor antagonist and methods of making the compounds.

BICYCLIC HETEROCYCLE DERIVATIVES AND USE THEREOF AS GPR119 MODULATORS

The present invention relates to Bicyclic Heterocycle Derivatives of Formula (I), compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a metaboli

BICYCLIC HETEROCYCLE DERIVATIVES AND THEIR USE AS GPCR MODULATORS

The present invention relates to Bicyclic Heterocycle Derivatives of Formula (I), compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a diabetic

BICYCLIC HETEROCYCLE DERIVATIVES AND METHODS OF USE THEREOF

The present invention relates to Bicyclic Heterocycle Derivatives, compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a diabetic complication,