16019-30-0

Basic information

• Product Name: 5-allylpyriMidine-4,6-diol
• Synonyms: 5-allylpyriMidine-4,6-diol;5-Allyl-4-hydroxy-1H-pyrimidin-6-one;5-ALLYL-6-HYDROXYPYRIMIDIN-4(3H)-ONE;4(3H)-Pyrimidinone, 6-hydroxy-5-(2-propen-1-yl)-
• CAS NO: 16019-30-0
• Molecular Formula: C₇H₈N₂O₂
• Molecular Weight: 152.15062
• Mol File: 16019-30-0.mol
• Article Data: 14

Chemical Properties

• Melting Point: 240 °C
• Boiling Point: 331.968°C at 760 mmHg
• Flash Point: 154.569°C
• Appearance: /
• Density: 1.299g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: 2-8°C
• PKA: 6.44±0.10(Predicted)
• CAS DataBase Reference: 5-allylpyriMidine-4,6-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-allylpyriMidine-4,6-diol(16019-30-0)
• EPA Substance Registry System: 5-allylpyriMidine-4,6-diol(16019-30-0)

Safety Data

• Hazardous Substances Data: 16019-30-0(Hazardous Substances Data)

Usage

General Description

5-allylpyrimidine-4,6-diol is a chemical compound with the molecular formula C7H8N2O2. It is a pyrimidine derivative that contains an allyl group (a group with the formula C3H5) and hydroxyl groups (OH) at the 4 and 6 positions on the pyrimidine ring. 5-allylpyriMidine-4,6-diol is used in various research and industrial applications, including as a building block for the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also used in the preparation of nucleosides and nucleotides, which are essential components of genetic material and play a crucial role in biological processes. The allyl group in 5-allylpyrimidine-4,6-diol contributes to its reactivity and potential for further modification in chemical reactions. Overall, this compound has significance in the field of organic and medicinal chemistry.

InChI:InChI=1/C7H8N2O2/c1-2-3-5-6(10)8-4-9-7(5)11/h2,4H,1,3H2,(H2,8,9,10,11)

Upstream product

• 2049-80-1 (2-propenyl)propanedioic acid diethyl ester 
• 6313-33-3 formamidine hydrochloride 
• 3473-63-0 formamidine acetic acid 
• 40637-56-7 dimethyl allylmalonate 
• 77287-34-4 formamide 
• 463-52-5 formamidine 

Downstream Products

• 16019-31-1 5-allyl-4,6-dichloropyrimidine 
• 212268-44-5 4-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine 
• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 
• 1456534-50-1 5-phenyl-1,2,3,4-tetrahydropyridazino[3,4-d]pyrimidine 
• 1456534-49-8 4-chloro-5-(2-chloroethyl)-6-phenylpyrimidine 
• 1456534-48-7 2-(4-chloro-6-phenylpyrimidin-5-yl)ethanol 
• 1456534-47-6 2-(4-chloro-6-phenylpyrimidin-5-yl)acetaldehyde 
• 1456534-46-5 4-chloro-5-(2,2-diethoxyethyl)-6-phenylpyrimidine 
• 1456534-31-8 1-(4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-(5-phenyl-3,4-dihydropyrimido[4,5-c]pyridazin-2(1H)-yl)ethane-1,2-dione 
• 1456534-45-4 1,3-dimethyl-5-phenyl-1,2,3,4-tetrahydropyridazino[3,4-d]pyrimidine 
• 1456534-44-3 1,3-dimethyl-5-phenyl-1,4-dihydropyridazino[3,4-d]pyrimidine 
• 1456534-30-7 1-(1,3-dimethyl-5-phenyl-3,4-dihydropyrimido[4,5-c]pyridazin-2(1H)-yl)-2-(4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione 

Relevant articles and documents

An improved synthesis of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine

[Figure not available: see fulltext.] An improved seven-step synthesis of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine from dimethyl malonate with 31% overall yield is described. The procedure is operationally simple and practical for the synthesis of the 4-chloro-7H-pyrrolo[2,3-d]pyrimidine building block.

Exploiting Atropisomerism to Increase the Target Selectivity of Kinase Inhibitors

Many biologically active molecules exist as rapidly interconverting atropisomeric mixtures. Whereas one atropisomer inhibits the desired target, the other can lead to off-target effects. Herein, we study atropisomerism as a possibility to improve the sele

Discovery of 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines as orally available g protein-coupled receptor 119 agonists

GPR119 is a 7-transmembrane receptor that is expressed in the enteroendocrine cells in the intestine and in the islets of Langerhans in the pancreas. Indolines and 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines were discovered as G protein-coupled receptor 119