160205-77-6Relevant academic research and scientific papers
A new and efficient method for the synthesis of bromosilanes from hydrosilanes using Br3CCOOEt/PdCl2 as the catalyst
Srithanakit, Phatsupha,Chavasiri, Warinthorn
experimental part, p. 2505 - 2507 (2011/05/09)
Bromosilanes were prepared conveniently and efficiently via the reaction of hydrosilanes and Br3CCOOEt in the presence of a catalytic amount of PdCl2 in refluxing THF over 15 min in high yields. The developed methodology was further applied for the one-pot synthesis of silyl ethers and silyl esters in excellent yields.
Effective silylation of carboxylic acids under solvent-free conditions with tert-butyldimethylsilyl chloride (TBDMSCL) and triisopropylsilyl chloride (TIPSCL)
Firouzabadi, Habib,Iranpoor, Naser,Shaterian, Hamid Reza
, p. 71 - 81 (2007/10/03)
Varions types of carboxylic acids can be converted effectively to their corresponding TBDMS and TIPS esters using TBDMSCI and TIPSCI in the presence of imidazole under solvent-free conditions. The advantage of this modified method in comparison with that reported by Corey is the elimination of DMF, which eliminates aqueous work-up. The method is not a time-consuming process and the reactions proceed spontaneously. By this method, absolute chemoselectivity for the protection of carboxylic acid functions in the presence of 2°, 3° hydroxyl groups are observed.
