160219-85-2

Upstream product

• 153821-50-2 Aquastatin A 
• 142955-98-4 ethyl 2,4-dimethoxy-6-pentadecanylbenzoate 
• 142956-02-3 ethyl 2,4-dihydroxy-6-pentadecanylbenzoate 
• 3686-57-5 2,4-dimethoxy-6-methylbenzoic acid 
• 487-69-4 2,4-dihydroxy-6-methylbenzaldehyde 
• 504-15-4 orcinol 
• 869996-08-7 2,4-bis-benzyloxy-6-pentadecyl-benzoic acid ethyl ester 
• 869996-09-8 2,4-bis(benzyloxy)-6-pentadecanylbenzoic acid 
• 869996-10-1 benzyl 4'-(2,4-dibenzyloxy-6-pentadecanylbenzoyloxy)-2'-hydroxy-6'-methylbenzoate 
• 57749-86-7 ethyl 2,4-dimethoxy-6-methylbenzoate 
• 38862-71-4 benzyl 2,4-dihydroxy-6-methylbenzoate 
• 480-64-8 orsellinic acid 
• 7149-90-8 2,4-dimethoxy-6-methyl-benzaldehyde 

Downstream Products

• 869996-11-2 benzyl 4'-(2,4-dihydroxy-6-pentadecanylbenzoyloxy)-2'-hydroxy-6'-methylbenzoate 
• 869996-12-3 benzyl 4'-(4-O-(2'',3''-di-O-acetyl-4'',6''-O-benzylidene-β-D-glucopyranosyl)-2-hydroxy-6-pentadecanylbenzoyloxy)-2'-hydroxy-6'-methylbenzoate 
• 869996-13-4 benzyl 4'-(4-O-(2'',3''-di-O-acetyl-4'',6''-O-benzylidene-β-D-glucopyranosyl)-2-benzyloxy-6-pentadecanylbenzoyloxy)-2'-benzyloxy-6'-methylbenzoate 

Relevant academic research and scientific papers

Isolation of the protein tyrosine phosphatase 1B inhibitory metabolite from the marine-derived fungus Cosmospora sp. SF-5060

In the course of bioassay-guided study on the EtOAc extract of a culture broth of the marine-derived fungus Cosmospora sp. SF-5060, aquastatin A (1) was isolated as a protein tyrosine phosphatase 1B (PTP1B) inhibitory component produced by the fungus. The

Total synthesis of CRM646-A and -B, two fungal glucuronides with potent heparinase inhibition activities

CRM646-A (1) and -B (2), two fungal glucuronides with a dimeric 2,4-dihydroxy-6-alkylbenzoic acid (orcinol p-depside) aglycone showing significant heparinase and telomerase inhibition activities, were synthesized for the first time. The successful approac