160235-14-3Relevant academic research and scientific papers
CrCl2 mediated addition of allylic halides or phosphates to N-protected α-amino aldehydes. Stereocontrolled synthesis of a new core for C2 symmetric HIV-protease inhibitors
Ciapetti, Paola,Falorni, Massimo,Taddei, Maurizio
, p. 7379 - 7390 (2007/10/03)
The addition of γ-monosubstituted allylchromium(III) reagents to N-protected α-amino aldehydes proceeds in a stereoconvergent manner in contrast with the case of the unsubstituted reagents, where the stereoselectivity depends on the nature of the group bo
CrCl2 mediated allylation of N-protected α-amino aldehydes. A versatile synthesis of polypeptides containing an hydroxyethylene isostere
Ciapetti, Paola,Taddei, Maurizio,Ulivi, Paola
, p. 3183 - 3186 (2007/10/02)
Differently substituted allylic bromides react with N-protected amino aldehydes to give intermediate products for the synthesis of hydroxyethylene dipeptide isosteres. The low stereoselectivity of this reaction can be improved using aldehydes protected wi
