160239-18-9Relevant articles and documents
The effect of the aromatic rings of taxol on biological activity and solution conformation: Synthesis and evaluation of saturated taxol and taxotere analogues
Boge,Himes,Vander Velde,Georg
, p. 3337 - 3343 (2007/10/02)
The synthesis and biological evaluation of novel cyclohexyl analogues of taxol and taxotere are detailed. 2-(Cyclohexylcarbonyl)-2-debenzoylbaccatin III (6) was prepared from baccatin III by hydrogenation. Subsequent coupling of 6 with N-t-BOC-3-[(tert-bu