16024-66-1

Basic information

• Product Name: 2,5,8,11,14-pentaoxahexadecan-16-oic acid
• Synonyms: 2,5,8,11,14-pentaoxahexadecan-16-oic acid;3,6,9,12,15-Pentaoxahexadecanoic acid;Einecs 240-163-7;Methyl-PEG4-CH2COOH;m-PEG5-CH3COOH
• CAS NO: 16024-66-1
• Molecular Formula: C₁₁H₂₂O₇
• Molecular Weight: 266.28818
• EINECS: 240-163-7
• Mol File: 16024-66-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 379.6°C at 760 mmHg
• Flash Point: 137.1°C
• Appearance: /
• Density: 1.125g/cm³
• Vapor Pressure: 8.24E-07mmHg at 25°C
• Refractive Index: 1.447
• PKA: 3.39±0.10(Predicted)
• CAS DataBase Reference: 2,5,8,11,14-pentaoxahexadecan-16-oic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5,8,11,14-pentaoxahexadecan-16-oic acid(16024-66-1)
• EPA Substance Registry System: 2,5,8,11,14-pentaoxahexadecan-16-oic acid(16024-66-1)

Safety Data

• Hazardous Substances Data: 16024-66-1(Hazardous Substances Data)

Usage

Description

2,5,8,11,14-Pentaoxahexadecan-16-oic acid is a unique organic compound characterized by its five oxygen atoms and a carboxylic acid group at the 16th position. This molecule exhibits properties that make it suitable for various applications across different industries.

Uses

Used in Pharmaceutical Industry:
2,5,8,11,14-Pentaoxahexadecan-16-oic acid is used as a building block for the synthesis of complex molecules, such as drugs and drug delivery systems, due to its unique structure and reactivity. The carboxylic acid group allows for easy conjugation with other molecules, while the multiple oxygen atoms provide opportunities for hydrogen bonding and other interactions.
Used in Cosmetics Industry:
In the cosmetics industry, 2,5,8,11,14-pentaoxahexadecan-16-oic acid is used as an emulsifier and stabilizer for various formulations. Its ability to form hydrogen bonds with other molecules helps to create stable emulsions and mixtures, improving the texture and performance of cosmetic products.
Used in Material Science:
2,5,8,11,14-Pentaoxahexadecan-16-oic acid can be utilized in the development of novel materials with specific properties. The presence of the carboxylic acid group and multiple oxygen atoms allows for the creation of polymers and copolymers with tailored characteristics, such as enhanced solubility, biodegradability, or mechanical strength.
Used in Chemical Synthesis:
As a versatile organic compound, 2,5,8,11,14-pentaoxahexadecan-16-oic acid can be employed in various chemical synthesis processes. Its carboxylic acid group can participate in reactions such as esterification, amidation, and other condensation reactions, enabling the creation of a wide range of derivatives with diverse applications.

InChI:InChI=1/C11H22O7/c1-14-2-3-15-4-5-16-6-7-17-8-9-18-10-11(12)13/h2-10H2,1H3,(H,12,13)

Upstream product

• 23783-42-8 tetraethylene glycol monomethyl ether 
• 79-08-3 bromoacetic acid 
• 112-60-7 Tetraethylene glycol 
• 52995-76-3 1-chloro-3,6,9-trioxadecane 
• 23778-52-1 3,6,9,12,15-pentaoxahexadecanol 

Downstream Products

• 1082737-41-4 C₁₇H₂₁F₅O₇ 
• 1359654-55-9 (triphenylphosphine)gold(I)(O₂CCH₂(OCH₂CH₂)4OCH₃) 
• 75427-81-5 3-Benzyloxypropylenbis(3,6,9,12,15-pentaoxahexadecanoat) 

Relevant articles and documents

BENZODICYCLOALKANE DERIVATIVE, PREPARATION METHOD AND USE THEREOF

It is provided herein a benzobicycloalkane derivative, and a preparation method and use thereof. In particular, it is provided herein a compound of Formula (I), or a pharmaceutically acceptable salt, stereoisomer or solvate thereof, a preparation method, and a use thereof in preparation of drugs for treating pain.

Preparation and application of monodisperse polyethylene glycol monomethyl ether modified propofol prodrug

Belonging to the field of organic chemistry and pharmaceutical chemicals, the invention discloses preparation and application of a monodisperse polyethylene glycol monomethyl ether modified propofol prodrug with a novel structure. Monodisperse polyethylene glycol monomethyl ether and propofol can be connected by an in-vivo degradable chemical bond to prepare a series of carbonic ester type and acetic ester type prodrugs respectively. By adjusting the length of the monodisperse polyethylene glycol monomethyl ether chain, the method can synthesize corresponding water-soluble propofol prodrugs, the longer the monodisperse polyethylene glycol monomethyl ether chain is, the better the water solubility is, along with the improvement of the water solubility, the prodrug can be made into aqueous solution preparations so as to avoid the defects of fat emulsion in propofol fat emulsions. The method provided by the invention has the advantages of simple reaction, mild conditions and low cost, andis convenient for industrial production.

Gold nanoparticles generated by thermolysis of "all-in-one" gold(i) carboxylate complexes

Consecutive synthesis methodologies for the preparation of the gold(i) carboxylates [(Ph3P)AuO2CCH2(OCH 2CH2)nOCH3] (n = 0-6) (6a-g) are reported, whereby selective mono-alkylation of diols HO(CH2CH 2O)nH (n = 0-6), Williamson ether synthesis and metal carboxylate (Ag, Au) formation are the key steps. Single crystal X-ray diffraction studies of 6a (n = 0) and 6b (n = 1) were carried out showing that the P-Au-O unit is essentially linear. These compounds were applied in the formation of gold nanoparticles (NP) by a thermally induced decomposition process and hence the addition of any further stabilizing and reducing reagents, respectively, is not required. The ethylene glycol functionalities, providing multiple donating capabilities, are able to stabilise the encapsulated gold colloids. The dependency of concentration, generation time and ethylene glycol chain lengths on the NP size and size distribution is discussed. Characterisation of the gold colloids was performed by TEM, UV/Vis spectroscopy and electron diffraction studies revealing that Au NP are formed with a size of 3.3 (±0.6) to 6.5 (±0.9) nm in p-xylene with a sharp size distribution. Additionally, a decomposition mechanism determined by TG-MS coupling experiments of the gold(i) precursors is reported showing that 1 st decarboxylation occurs followed by the cleavage of the Au-PPh 3 bond and finally release of ethylene glycol fragments to give Au-NP and the appropriate organics. The Royal Society of Chemistry 2012.