23783-42-8Relevant articles and documents
Detecting a transition-metal ammine at tailored surfaces
Iqbal, Sayeedha,Kremer, Felix J.B.,Ringsdorf, Helmut,Steinbeck, Martin,Stoddart, J. Fraser,Shen, Jie,Tinker, Nigel D.
, p. 1147 - 1154 (1997)
The fabrication of surfaces by forming Langmuir films, which incorporate amphiphiles containing hydrophilic 18-crown-6 (18C6) derivatives, at a gas/water interface is described. These Langmuir films can be transferred to a hydrophobised quartz crystal microbalance (QCM), using the Langmuir-Blodgett technique. The QCM response has been measured in aqueous solution as a function of the concentration of the transition metal complex [Co(NH3)6]Cl3 which was injected into a vial in which the film-coated QCM had been immersed. By comparing various surfaces covered with hydrophilic polyether and hydroxy functions and hydrophobic methyl groups, and by varying the composition of the films so as to increase the separation between the 18C6 macrocycles, it has been demonstrated that surfaces can be tailored that will enhance the binding of the [Co(NH3)6]3+ trications.
Monodisperse polyethylene glycol “brushes” with enhanced lipophilicity, and thermo and plasma stability
Li, Yu,Wang, Xuemeng,Chen, Yongping,Yang, Zhigang,Jiang, Zhong-Xing
supporting information, p. 1895 - 1898 (2019/05/02)
A convenient strategy was developed for highly branched and multifunctionalized peptidic monodisperse polyethylene glycol “brushes”, which exhibit remarkable physicochemical and biological properties and potential as versatile biomaterials.
INHIBITORS OF HEPATITIS C VIRUS POLYMERASE
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Paragraph 328; 331, (2016/10/11)
The present invention provides, among other things, compounds represented by the general Formula I: (I) and pharmaceutically acceptable salts thereof, wherein L and A (and further substituents) are as defined in classes and subclasses herein and compositions (e.g., pharmaceutical compositions) comprising such compounds, which compounds are useful as inhibitors of hepatitis C virus polymerase, and thus are useful, for example, as medicaments for the treatment of HCV infection.
