1602827-88-2Relevant academic research and scientific papers
A concise [C+NC+CC] coupling-enabled synthesis of kaitocephalin
Garner, Philip,Weerasinghe, Laksiri,Van Houten, Ian,Hu, Jieyu
, p. 4908 - 4910 (2014)
A 15-step synthesis of the iGluR antagonist kaitocephalin from aspartic acid is reported. The linchpin pyrrolidine ring of the target molecule is efficiently assembled with in a single operation via an asymmetric [C+NC+CC] reaction.
